node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv1435c | xerC | Rv1435c | Rv2894c | Rv1435c, (MTCY493.19), len: 202 aa. Probable conserved Pro-, Gly-, Val-rich secreted protein (see citation below) with a N-terminal signal sequence. Similar at C-terminus to AF017099|AF017099_1 Mycobacterium tuberculosis pGB1 (87 aa), FASTA scores: opt: 550, E(): 2.3e-17, (97.7% identity in 86 aa overlap). Shows some similarity to N-terminus of CPN_DROME|Q02910 calphotin. Drosophila melanogaster (865 aa), FASTA scores: opt: 266,E(): 2.5e-05, (37.2% identity in 191 aa overlap). Contains at least five 7 aa imperfect repeats. Also shows similarity to other Mycobacterium tuberculosis prote [...] | Probable integrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity). | 0.780 |
Rv2646 | Rv3226c | Rv2646 | Rv3226c | Probable integrase; Rv2646, (MTCY441.16), len: 332 aa. Probable integrase, similar to others e.g. P06723|VINT_BP186|int integrase from Bacteriophage 186 (336 aa)s FASTA scores: opt: 198, E(): 6.3e-05, (30.45% identity in 138 aa overlap). Could be belong to the 'phage' integrase family. | Conserved hypothetical protein; Rv3226c, (MTCY20B11.01c), len: 252 aa. Conserved hypothetical protein, similar to various hypothetical bacterial proteins e.g. Q9CCI2|ML0793 putative bacteriophage protein from Mycobacterium leprae (252 aa),FASTA scores: opt: 1183, E(): 3.8e-68, (70.65% identity in 252 aa overlap); BAB54183|MLR7795 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (369 aa), FASTA scores: opt: 417, E(): 2.9e-19, (33.75% identity in 252 aa overlap); O64131 YOQW protein from Bacteriophage SPBc2 (224 aa), FASTA scores: opt: 413, E(): 3.4e-19, (38.5% identity in 2 [...] | 0.456 |
Rv2646 | Rv3242c | Rv2646 | Rv3242c | Probable integrase; Rv2646, (MTCY441.16), len: 332 aa. Probable integrase, similar to others e.g. P06723|VINT_BP186|int integrase from Bacteriophage 186 (336 aa)s FASTA scores: opt: 198, E(): 6.3e-05, (30.45% identity in 138 aa overlap). Could be belong to the 'phage' integrase family. | Conserved hypothetical protein; Rv3242c, (MTCY20B11.17c), len: 213 aa. Conserved hypothetical protein, highly similar in N-terminus to Q9CCI9|ML0776 hypothetical protein from Mycobacterium leprae (85 aa), FASTA scores: opt: 324, E(): 1.7e-13,(78.1% identity in 64 aa overlap). Also similar to Q9RUJ7|DR1389 putative competence protein COMF from Deinococcus radiodurans (219 aa), FASTA scores: opt: 223,E(): 6.3e-07, (35.8% identity in 215 aa overlap); BAB50338|MLL3453 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (240 aa), FASTA scores: opt: 218, E(): 1.4e-06, (28.5% identi [...] | 0.467 |
Rv2646 | apt | Rv2646 | Rv2584c | Probable integrase; Rv2646, (MTCY441.16), len: 332 aa. Probable integrase, similar to others e.g. P06723|VINT_BP186|int integrase from Bacteriophage 186 (336 aa)s FASTA scores: opt: 198, E(): 6.3e-05, (30.45% identity in 138 aa overlap). Could be belong to the 'phage' integrase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.459 |
Rv2646 | ftsK | Rv2646 | Rv2748c | Probable integrase; Rv2646, (MTCY441.16), len: 332 aa. Probable integrase, similar to others e.g. P06723|VINT_BP186|int integrase from Bacteriophage 186 (336 aa)s FASTA scores: opt: 198, E(): 6.3e-05, (30.45% identity in 138 aa overlap). Could be belong to the 'phage' integrase family. | Possible cell division transmembrane protein FtsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). | 0.682 |
Rv2646 | tyrA | Rv2646 | Rv3754 | Probable integrase; Rv2646, (MTCY441.16), len: 332 aa. Probable integrase, similar to others e.g. P06723|VINT_BP186|int integrase from Bacteriophage 186 (336 aa)s FASTA scores: opt: 198, E(): 6.3e-05, (30.45% identity in 138 aa overlap). Could be belong to the 'phage' integrase family. | Prephenate dehydrogenase TyrA (PDH) (hydroxyphenylpyruvate synthase); Catalyzes the NAD(+)-dependent conversion of prephenate to p- hydroxyphenylpyruvate, with the elimination of carbon dioxide. Is a key regulatory enzyme in tyrosine biosynthesis. Displays no chorismate mutase (CM) activity, in contrast to TyrA from E.coli and some other bacteria, that are bifunctional and possess a CM domain. | 0.495 |
Rv2646 | whiA | Rv2646 | Rv1423 | Probable integrase; Rv2646, (MTCY441.16), len: 332 aa. Probable integrase, similar to others e.g. P06723|VINT_BP186|int integrase from Bacteriophage 186 (336 aa)s FASTA scores: opt: 198, E(): 6.3e-05, (30.45% identity in 138 aa overlap). Could be belong to the 'phage' integrase family. | Probable transcriptional regulatory protein WhiA; Involved in cell division and chromosome segregation. | 0.434 |
Rv2646 | xerC | Rv2646 | Rv2894c | Probable integrase; Rv2646, (MTCY441.16), len: 332 aa. Probable integrase, similar to others e.g. P06723|VINT_BP186|int integrase from Bacteriophage 186 (336 aa)s FASTA scores: opt: 198, E(): 6.3e-05, (30.45% identity in 138 aa overlap). Could be belong to the 'phage' integrase family. | Probable integrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity). | 0.798 |
Rv3226c | Rv2646 | Rv3226c | Rv2646 | Conserved hypothetical protein; Rv3226c, (MTCY20B11.01c), len: 252 aa. Conserved hypothetical protein, similar to various hypothetical bacterial proteins e.g. Q9CCI2|ML0793 putative bacteriophage protein from Mycobacterium leprae (252 aa),FASTA scores: opt: 1183, E(): 3.8e-68, (70.65% identity in 252 aa overlap); BAB54183|MLR7795 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (369 aa), FASTA scores: opt: 417, E(): 2.9e-19, (33.75% identity in 252 aa overlap); O64131 YOQW protein from Bacteriophage SPBc2 (224 aa), FASTA scores: opt: 413, E(): 3.4e-19, (38.5% identity in 2 [...] | Probable integrase; Rv2646, (MTCY441.16), len: 332 aa. Probable integrase, similar to others e.g. P06723|VINT_BP186|int integrase from Bacteriophage 186 (336 aa)s FASTA scores: opt: 198, E(): 6.3e-05, (30.45% identity in 138 aa overlap). Could be belong to the 'phage' integrase family. | 0.456 |
Rv3226c | Rv3242c | Rv3226c | Rv3242c | Conserved hypothetical protein; Rv3226c, (MTCY20B11.01c), len: 252 aa. Conserved hypothetical protein, similar to various hypothetical bacterial proteins e.g. Q9CCI2|ML0793 putative bacteriophage protein from Mycobacterium leprae (252 aa),FASTA scores: opt: 1183, E(): 3.8e-68, (70.65% identity in 252 aa overlap); BAB54183|MLR7795 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (369 aa), FASTA scores: opt: 417, E(): 2.9e-19, (33.75% identity in 252 aa overlap); O64131 YOQW protein from Bacteriophage SPBc2 (224 aa), FASTA scores: opt: 413, E(): 3.4e-19, (38.5% identity in 2 [...] | Conserved hypothetical protein; Rv3242c, (MTCY20B11.17c), len: 213 aa. Conserved hypothetical protein, highly similar in N-terminus to Q9CCI9|ML0776 hypothetical protein from Mycobacterium leprae (85 aa), FASTA scores: opt: 324, E(): 1.7e-13,(78.1% identity in 64 aa overlap). Also similar to Q9RUJ7|DR1389 putative competence protein COMF from Deinococcus radiodurans (219 aa), FASTA scores: opt: 223,E(): 6.3e-07, (35.8% identity in 215 aa overlap); BAB50338|MLL3453 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (240 aa), FASTA scores: opt: 218, E(): 1.4e-06, (28.5% identi [...] | 0.457 |
Rv3226c | xerC | Rv3226c | Rv2894c | Conserved hypothetical protein; Rv3226c, (MTCY20B11.01c), len: 252 aa. Conserved hypothetical protein, similar to various hypothetical bacterial proteins e.g. Q9CCI2|ML0793 putative bacteriophage protein from Mycobacterium leprae (252 aa),FASTA scores: opt: 1183, E(): 3.8e-68, (70.65% identity in 252 aa overlap); BAB54183|MLR7795 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (369 aa), FASTA scores: opt: 417, E(): 2.9e-19, (33.75% identity in 252 aa overlap); O64131 YOQW protein from Bacteriophage SPBc2 (224 aa), FASTA scores: opt: 413, E(): 3.4e-19, (38.5% identity in 2 [...] | Probable integrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity). | 0.775 |
Rv3242c | Rv2646 | Rv3242c | Rv2646 | Conserved hypothetical protein; Rv3242c, (MTCY20B11.17c), len: 213 aa. Conserved hypothetical protein, highly similar in N-terminus to Q9CCI9|ML0776 hypothetical protein from Mycobacterium leprae (85 aa), FASTA scores: opt: 324, E(): 1.7e-13,(78.1% identity in 64 aa overlap). Also similar to Q9RUJ7|DR1389 putative competence protein COMF from Deinococcus radiodurans (219 aa), FASTA scores: opt: 223,E(): 6.3e-07, (35.8% identity in 215 aa overlap); BAB50338|MLL3453 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (240 aa), FASTA scores: opt: 218, E(): 1.4e-06, (28.5% identi [...] | Probable integrase; Rv2646, (MTCY441.16), len: 332 aa. Probable integrase, similar to others e.g. P06723|VINT_BP186|int integrase from Bacteriophage 186 (336 aa)s FASTA scores: opt: 198, E(): 6.3e-05, (30.45% identity in 138 aa overlap). Could be belong to the 'phage' integrase family. | 0.467 |
Rv3242c | Rv3226c | Rv3242c | Rv3226c | Conserved hypothetical protein; Rv3242c, (MTCY20B11.17c), len: 213 aa. Conserved hypothetical protein, highly similar in N-terminus to Q9CCI9|ML0776 hypothetical protein from Mycobacterium leprae (85 aa), FASTA scores: opt: 324, E(): 1.7e-13,(78.1% identity in 64 aa overlap). Also similar to Q9RUJ7|DR1389 putative competence protein COMF from Deinococcus radiodurans (219 aa), FASTA scores: opt: 223,E(): 6.3e-07, (35.8% identity in 215 aa overlap); BAB50338|MLL3453 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (240 aa), FASTA scores: opt: 218, E(): 1.4e-06, (28.5% identi [...] | Conserved hypothetical protein; Rv3226c, (MTCY20B11.01c), len: 252 aa. Conserved hypothetical protein, similar to various hypothetical bacterial proteins e.g. Q9CCI2|ML0793 putative bacteriophage protein from Mycobacterium leprae (252 aa),FASTA scores: opt: 1183, E(): 3.8e-68, (70.65% identity in 252 aa overlap); BAB54183|MLR7795 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (369 aa), FASTA scores: opt: 417, E(): 2.9e-19, (33.75% identity in 252 aa overlap); O64131 YOQW protein from Bacteriophage SPBc2 (224 aa), FASTA scores: opt: 413, E(): 3.4e-19, (38.5% identity in 2 [...] | 0.457 |
Rv3242c | apt | Rv3242c | Rv2584c | Conserved hypothetical protein; Rv3242c, (MTCY20B11.17c), len: 213 aa. Conserved hypothetical protein, highly similar in N-terminus to Q9CCI9|ML0776 hypothetical protein from Mycobacterium leprae (85 aa), FASTA scores: opt: 324, E(): 1.7e-13,(78.1% identity in 64 aa overlap). Also similar to Q9RUJ7|DR1389 putative competence protein COMF from Deinococcus radiodurans (219 aa), FASTA scores: opt: 223,E(): 6.3e-07, (35.8% identity in 215 aa overlap); BAB50338|MLL3453 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (240 aa), FASTA scores: opt: 218, E(): 1.4e-06, (28.5% identi [...] | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.808 |
Rv3242c | tyrA | Rv3242c | Rv3754 | Conserved hypothetical protein; Rv3242c, (MTCY20B11.17c), len: 213 aa. Conserved hypothetical protein, highly similar in N-terminus to Q9CCI9|ML0776 hypothetical protein from Mycobacterium leprae (85 aa), FASTA scores: opt: 324, E(): 1.7e-13,(78.1% identity in 64 aa overlap). Also similar to Q9RUJ7|DR1389 putative competence protein COMF from Deinococcus radiodurans (219 aa), FASTA scores: opt: 223,E(): 6.3e-07, (35.8% identity in 215 aa overlap); BAB50338|MLL3453 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (240 aa), FASTA scores: opt: 218, E(): 1.4e-06, (28.5% identi [...] | Prephenate dehydrogenase TyrA (PDH) (hydroxyphenylpyruvate synthase); Catalyzes the NAD(+)-dependent conversion of prephenate to p- hydroxyphenylpyruvate, with the elimination of carbon dioxide. Is a key regulatory enzyme in tyrosine biosynthesis. Displays no chorismate mutase (CM) activity, in contrast to TyrA from E.coli and some other bacteria, that are bifunctional and possess a CM domain. | 0.833 |
Rv3242c | whiA | Rv3242c | Rv1423 | Conserved hypothetical protein; Rv3242c, (MTCY20B11.17c), len: 213 aa. Conserved hypothetical protein, highly similar in N-terminus to Q9CCI9|ML0776 hypothetical protein from Mycobacterium leprae (85 aa), FASTA scores: opt: 324, E(): 1.7e-13,(78.1% identity in 64 aa overlap). Also similar to Q9RUJ7|DR1389 putative competence protein COMF from Deinococcus radiodurans (219 aa), FASTA scores: opt: 223,E(): 6.3e-07, (35.8% identity in 215 aa overlap); BAB50338|MLL3453 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (240 aa), FASTA scores: opt: 218, E(): 1.4e-06, (28.5% identi [...] | Probable transcriptional regulatory protein WhiA; Involved in cell division and chromosome segregation. | 0.461 |
Rv3242c | xerC | Rv3242c | Rv2894c | Conserved hypothetical protein; Rv3242c, (MTCY20B11.17c), len: 213 aa. Conserved hypothetical protein, highly similar in N-terminus to Q9CCI9|ML0776 hypothetical protein from Mycobacterium leprae (85 aa), FASTA scores: opt: 324, E(): 1.7e-13,(78.1% identity in 64 aa overlap). Also similar to Q9RUJ7|DR1389 putative competence protein COMF from Deinococcus radiodurans (219 aa), FASTA scores: opt: 223,E(): 6.3e-07, (35.8% identity in 215 aa overlap); BAB50338|MLL3453 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (240 aa), FASTA scores: opt: 218, E(): 1.4e-06, (28.5% identi [...] | Probable integrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity). | 0.902 |
apt | Rv2646 | Rv2584c | Rv2646 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Probable integrase; Rv2646, (MTCY441.16), len: 332 aa. Probable integrase, similar to others e.g. P06723|VINT_BP186|int integrase from Bacteriophage 186 (336 aa)s FASTA scores: opt: 198, E(): 6.3e-05, (30.45% identity in 138 aa overlap). Could be belong to the 'phage' integrase family. | 0.459 |
apt | Rv3242c | Rv2584c | Rv3242c | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Conserved hypothetical protein; Rv3242c, (MTCY20B11.17c), len: 213 aa. Conserved hypothetical protein, highly similar in N-terminus to Q9CCI9|ML0776 hypothetical protein from Mycobacterium leprae (85 aa), FASTA scores: opt: 324, E(): 1.7e-13,(78.1% identity in 64 aa overlap). Also similar to Q9RUJ7|DR1389 putative competence protein COMF from Deinococcus radiodurans (219 aa), FASTA scores: opt: 223,E(): 6.3e-07, (35.8% identity in 215 aa overlap); BAB50338|MLL3453 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (240 aa), FASTA scores: opt: 218, E(): 1.4e-06, (28.5% identi [...] | 0.808 |
apt | tyrA | Rv2584c | Rv3754 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Prephenate dehydrogenase TyrA (PDH) (hydroxyphenylpyruvate synthase); Catalyzes the NAD(+)-dependent conversion of prephenate to p- hydroxyphenylpyruvate, with the elimination of carbon dioxide. Is a key regulatory enzyme in tyrosine biosynthesis. Displays no chorismate mutase (CM) activity, in contrast to TyrA from E.coli and some other bacteria, that are bifunctional and possess a CM domain. | 0.816 |