node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv2275 | Rv2954c | Rv2275 | Rv2954c | Conserved hypothetical protein; Involved in the biosynthesis of mycocyclosin. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP-independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Tyr-L-Tyr) (cYY) from L- tyrosyl-tRNA(Tyr). Can incorporate various nonpolar residues, such as L-phenylalanine, L-leucine, L-tyrosine and L-methionine, and to a much lesser extent L-alanine, into cyclodipeptides. Cyclodipeptides synthesized by Rv2275 always c [...] | Hypothetical protein; Rv2954c, (MTCY349.36), len: 241 aa. Hypothetical unknown protein. Equivalent to AAK47354 from Mycobacterium tuberculosis strain CDC1551 (199 aa) but longer 42 aa. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.865 |
Rv2275 | Rv3727 | Rv2275 | Rv3727 | Conserved hypothetical protein; Involved in the biosynthesis of mycocyclosin. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP-independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Tyr-L-Tyr) (cYY) from L- tyrosyl-tRNA(Tyr). Can incorporate various nonpolar residues, such as L-phenylalanine, L-leucine, L-tyrosine and L-methionine, and to a much lesser extent L-alanine, into cyclodipeptides. Cyclodipeptides synthesized by Rv2275 always c [...] | Rv3727, (MTV025.075), len: 602 aa. Possible oxidoreductase, similar to several plants phytoene dehydrogenases/desaturases e.g. Q9HSE1|CRTI3|VNG0277G phytoene dehydrogenase from Halobacterium sp. strain NRC-1 (541 aa), FASTA scores: opt: 299, E(): 1.1e-10, (29.85% identity in 576 aa overlap); Q9FZL6|CITPDS1 phytoene desaturase from Citrus unshiu (Satsuma orange) (553 aa),FASTA scores: opt: 164, E(): 0.018, (24.2% identity in 434 aa overlap); Q07356|CRTI_ARATH|PDS|AT4G14210|DL3145c phytoene dehydrogenase precursor from Arabidopsis thaliana (Mouse-ear cress) (566 aa), FASTA scores: opt: 1 [...] | 0.622 |
Rv2275 | lppY | Rv2275 | Rv2999 | Conserved hypothetical protein; Involved in the biosynthesis of mycocyclosin. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP-independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Tyr-L-Tyr) (cYY) from L- tyrosyl-tRNA(Tyr). Can incorporate various nonpolar residues, such as L-phenylalanine, L-leucine, L-tyrosine and L-methionine, and to a much lesser extent L-alanine, into cyclodipeptides. Cyclodipeptides synthesized by Rv2275 always c [...] | Rv2999, (MTV012.13), len: 321 aa. Probable lppY,conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c putative lipoprotein from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 uncharacterized conserved protein similar to LPPY/LPQO of Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa),FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c putative lipoprotein (fragment) from Streptomyces coelicolor (146 aa) [...] | 0.426 |
Rv2954c | Rv2275 | Rv2954c | Rv2275 | Hypothetical protein; Rv2954c, (MTCY349.36), len: 241 aa. Hypothetical unknown protein. Equivalent to AAK47354 from Mycobacterium tuberculosis strain CDC1551 (199 aa) but longer 42 aa. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Conserved hypothetical protein; Involved in the biosynthesis of mycocyclosin. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP-independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Tyr-L-Tyr) (cYY) from L- tyrosyl-tRNA(Tyr). Can incorporate various nonpolar residues, such as L-phenylalanine, L-leucine, L-tyrosine and L-methionine, and to a much lesser extent L-alanine, into cyclodipeptides. Cyclodipeptides synthesized by Rv2275 always c [...] | 0.865 |
Rv2954c | Rv3727 | Rv2954c | Rv3727 | Hypothetical protein; Rv2954c, (MTCY349.36), len: 241 aa. Hypothetical unknown protein. Equivalent to AAK47354 from Mycobacterium tuberculosis strain CDC1551 (199 aa) but longer 42 aa. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv3727, (MTV025.075), len: 602 aa. Possible oxidoreductase, similar to several plants phytoene dehydrogenases/desaturases e.g. Q9HSE1|CRTI3|VNG0277G phytoene dehydrogenase from Halobacterium sp. strain NRC-1 (541 aa), FASTA scores: opt: 299, E(): 1.1e-10, (29.85% identity in 576 aa overlap); Q9FZL6|CITPDS1 phytoene desaturase from Citrus unshiu (Satsuma orange) (553 aa),FASTA scores: opt: 164, E(): 0.018, (24.2% identity in 434 aa overlap); Q07356|CRTI_ARATH|PDS|AT4G14210|DL3145c phytoene dehydrogenase precursor from Arabidopsis thaliana (Mouse-ear cress) (566 aa), FASTA scores: opt: 1 [...] | 0.753 |
Rv2954c | lppY | Rv2954c | Rv2999 | Hypothetical protein; Rv2954c, (MTCY349.36), len: 241 aa. Hypothetical unknown protein. Equivalent to AAK47354 from Mycobacterium tuberculosis strain CDC1551 (199 aa) but longer 42 aa. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv2999, (MTV012.13), len: 321 aa. Probable lppY,conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c putative lipoprotein from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 uncharacterized conserved protein similar to LPPY/LPQO of Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa),FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c putative lipoprotein (fragment) from Streptomyces coelicolor (146 aa) [...] | 0.466 |
Rv2998A | Rv3000 | Rv2998A | Rv3000 | Rv2998A, len: 67 aa. Probable conserved hypothetical protein, (possibly gene fragment), highly similar to central part of two-component sensor proteins e.g. O07777|Rv0601c|MTCY19H5.21 two component sensor (fragment) from Mycobacterium tuberculosis (156 aa), FASTA scores: opt: 212, E(): 3.7e-09, (58.2% identity in 67 aa overlap); Q9L2B6|SC8F4.08 probable two-component sensor kinase from Streptomyces coelicolor (478 aa), FASTA scores: opt: 193,E(): 2.6e-07, (47.05% identity in 68 aa overlap); etc. | Rv3000, (MTV012.14), len: 219 aa. Possible conserved transmembrane protein, similar to various membrane proteins e.g. P77307|YBBM_ECOLI|B0491 hypothetical 28.2 KDA protein (potential integral membrane protein) from Escherichia coli strain K12 (259 aa), FASTA scores: opt: 292, E(): 3.1e-11,(30.25% identity in 218 aa overlap); N-terminus of Q9BJF3 putative ABC transporter (fragment) from Sterkiella histriomuscorum (1319 aa), FASTA scores: opt: 274, E(): 1.3e-09, (39.6% identity in 101 aa overlap); Q9C9W0|T23K23.21 putative ABC transporter from Arabidopsis thaliana (Mouse-ear cress) (263 [...] | 0.450 |
Rv2998A | lppY | Rv2998A | Rv2999 | Rv2998A, len: 67 aa. Probable conserved hypothetical protein, (possibly gene fragment), highly similar to central part of two-component sensor proteins e.g. O07777|Rv0601c|MTCY19H5.21 two component sensor (fragment) from Mycobacterium tuberculosis (156 aa), FASTA scores: opt: 212, E(): 3.7e-09, (58.2% identity in 67 aa overlap); Q9L2B6|SC8F4.08 probable two-component sensor kinase from Streptomyces coelicolor (478 aa), FASTA scores: opt: 193,E(): 2.6e-07, (47.05% identity in 68 aa overlap); etc. | Rv2999, (MTV012.13), len: 321 aa. Probable lppY,conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c putative lipoprotein from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 uncharacterized conserved protein similar to LPPY/LPQO of Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa),FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c putative lipoprotein (fragment) from Streptomyces coelicolor (146 aa) [...] | 0.518 |
Rv3000 | Rv2998A | Rv3000 | Rv2998A | Rv3000, (MTV012.14), len: 219 aa. Possible conserved transmembrane protein, similar to various membrane proteins e.g. P77307|YBBM_ECOLI|B0491 hypothetical 28.2 KDA protein (potential integral membrane protein) from Escherichia coli strain K12 (259 aa), FASTA scores: opt: 292, E(): 3.1e-11,(30.25% identity in 218 aa overlap); N-terminus of Q9BJF3 putative ABC transporter (fragment) from Sterkiella histriomuscorum (1319 aa), FASTA scores: opt: 274, E(): 1.3e-09, (39.6% identity in 101 aa overlap); Q9C9W0|T23K23.21 putative ABC transporter from Arabidopsis thaliana (Mouse-ear cress) (263 [...] | Rv2998A, len: 67 aa. Probable conserved hypothetical protein, (possibly gene fragment), highly similar to central part of two-component sensor proteins e.g. O07777|Rv0601c|MTCY19H5.21 two component sensor (fragment) from Mycobacterium tuberculosis (156 aa), FASTA scores: opt: 212, E(): 3.7e-09, (58.2% identity in 67 aa overlap); Q9L2B6|SC8F4.08 probable two-component sensor kinase from Streptomyces coelicolor (478 aa), FASTA scores: opt: 193,E(): 2.6e-07, (47.05% identity in 68 aa overlap); etc. | 0.450 |
Rv3000 | lppY | Rv3000 | Rv2999 | Rv3000, (MTV012.14), len: 219 aa. Possible conserved transmembrane protein, similar to various membrane proteins e.g. P77307|YBBM_ECOLI|B0491 hypothetical 28.2 KDA protein (potential integral membrane protein) from Escherichia coli strain K12 (259 aa), FASTA scores: opt: 292, E(): 3.1e-11,(30.25% identity in 218 aa overlap); N-terminus of Q9BJF3 putative ABC transporter (fragment) from Sterkiella histriomuscorum (1319 aa), FASTA scores: opt: 274, E(): 1.3e-09, (39.6% identity in 101 aa overlap); Q9C9W0|T23K23.21 putative ABC transporter from Arabidopsis thaliana (Mouse-ear cress) (263 [...] | Rv2999, (MTV012.13), len: 321 aa. Probable lppY,conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c putative lipoprotein from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 uncharacterized conserved protein similar to LPPY/LPQO of Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa),FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c putative lipoprotein (fragment) from Streptomyces coelicolor (146 aa) [...] | 0.681 |
Rv3727 | Rv2275 | Rv3727 | Rv2275 | Rv3727, (MTV025.075), len: 602 aa. Possible oxidoreductase, similar to several plants phytoene dehydrogenases/desaturases e.g. Q9HSE1|CRTI3|VNG0277G phytoene dehydrogenase from Halobacterium sp. strain NRC-1 (541 aa), FASTA scores: opt: 299, E(): 1.1e-10, (29.85% identity in 576 aa overlap); Q9FZL6|CITPDS1 phytoene desaturase from Citrus unshiu (Satsuma orange) (553 aa),FASTA scores: opt: 164, E(): 0.018, (24.2% identity in 434 aa overlap); Q07356|CRTI_ARATH|PDS|AT4G14210|DL3145c phytoene dehydrogenase precursor from Arabidopsis thaliana (Mouse-ear cress) (566 aa), FASTA scores: opt: 1 [...] | Conserved hypothetical protein; Involved in the biosynthesis of mycocyclosin. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP-independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Tyr-L-Tyr) (cYY) from L- tyrosyl-tRNA(Tyr). Can incorporate various nonpolar residues, such as L-phenylalanine, L-leucine, L-tyrosine and L-methionine, and to a much lesser extent L-alanine, into cyclodipeptides. Cyclodipeptides synthesized by Rv2275 always c [...] | 0.622 |
Rv3727 | Rv2954c | Rv3727 | Rv2954c | Rv3727, (MTV025.075), len: 602 aa. Possible oxidoreductase, similar to several plants phytoene dehydrogenases/desaturases e.g. Q9HSE1|CRTI3|VNG0277G phytoene dehydrogenase from Halobacterium sp. strain NRC-1 (541 aa), FASTA scores: opt: 299, E(): 1.1e-10, (29.85% identity in 576 aa overlap); Q9FZL6|CITPDS1 phytoene desaturase from Citrus unshiu (Satsuma orange) (553 aa),FASTA scores: opt: 164, E(): 0.018, (24.2% identity in 434 aa overlap); Q07356|CRTI_ARATH|PDS|AT4G14210|DL3145c phytoene dehydrogenase precursor from Arabidopsis thaliana (Mouse-ear cress) (566 aa), FASTA scores: opt: 1 [...] | Hypothetical protein; Rv2954c, (MTCY349.36), len: 241 aa. Hypothetical unknown protein. Equivalent to AAK47354 from Mycobacterium tuberculosis strain CDC1551 (199 aa) but longer 42 aa. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.753 |
Rv3727 | lppY | Rv3727 | Rv2999 | Rv3727, (MTV025.075), len: 602 aa. Possible oxidoreductase, similar to several plants phytoene dehydrogenases/desaturases e.g. Q9HSE1|CRTI3|VNG0277G phytoene dehydrogenase from Halobacterium sp. strain NRC-1 (541 aa), FASTA scores: opt: 299, E(): 1.1e-10, (29.85% identity in 576 aa overlap); Q9FZL6|CITPDS1 phytoene desaturase from Citrus unshiu (Satsuma orange) (553 aa),FASTA scores: opt: 164, E(): 0.018, (24.2% identity in 434 aa overlap); Q07356|CRTI_ARATH|PDS|AT4G14210|DL3145c phytoene dehydrogenase precursor from Arabidopsis thaliana (Mouse-ear cress) (566 aa), FASTA scores: opt: 1 [...] | Rv2999, (MTV012.13), len: 321 aa. Probable lppY,conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c putative lipoprotein from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 uncharacterized conserved protein similar to LPPY/LPQO of Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa),FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c putative lipoprotein (fragment) from Streptomyces coelicolor (146 aa) [...] | 0.402 |
lppY | Rv2275 | Rv2999 | Rv2275 | Rv2999, (MTV012.13), len: 321 aa. Probable lppY,conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c putative lipoprotein from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 uncharacterized conserved protein similar to LPPY/LPQO of Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa),FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c putative lipoprotein (fragment) from Streptomyces coelicolor (146 aa) [...] | Conserved hypothetical protein; Involved in the biosynthesis of mycocyclosin. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP-independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Tyr-L-Tyr) (cYY) from L- tyrosyl-tRNA(Tyr). Can incorporate various nonpolar residues, such as L-phenylalanine, L-leucine, L-tyrosine and L-methionine, and to a much lesser extent L-alanine, into cyclodipeptides. Cyclodipeptides synthesized by Rv2275 always c [...] | 0.426 |
lppY | Rv2954c | Rv2999 | Rv2954c | Rv2999, (MTV012.13), len: 321 aa. Probable lppY,conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c putative lipoprotein from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 uncharacterized conserved protein similar to LPPY/LPQO of Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa),FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c putative lipoprotein (fragment) from Streptomyces coelicolor (146 aa) [...] | Hypothetical protein; Rv2954c, (MTCY349.36), len: 241 aa. Hypothetical unknown protein. Equivalent to AAK47354 from Mycobacterium tuberculosis strain CDC1551 (199 aa) but longer 42 aa. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.466 |
lppY | Rv2998A | Rv2999 | Rv2998A | Rv2999, (MTV012.13), len: 321 aa. Probable lppY,conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c putative lipoprotein from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 uncharacterized conserved protein similar to LPPY/LPQO of Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa),FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c putative lipoprotein (fragment) from Streptomyces coelicolor (146 aa) [...] | Rv2998A, len: 67 aa. Probable conserved hypothetical protein, (possibly gene fragment), highly similar to central part of two-component sensor proteins e.g. O07777|Rv0601c|MTCY19H5.21 two component sensor (fragment) from Mycobacterium tuberculosis (156 aa), FASTA scores: opt: 212, E(): 3.7e-09, (58.2% identity in 67 aa overlap); Q9L2B6|SC8F4.08 probable two-component sensor kinase from Streptomyces coelicolor (478 aa), FASTA scores: opt: 193,E(): 2.6e-07, (47.05% identity in 68 aa overlap); etc. | 0.518 |
lppY | Rv3000 | Rv2999 | Rv3000 | Rv2999, (MTV012.13), len: 321 aa. Probable lppY,conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c putative lipoprotein from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 uncharacterized conserved protein similar to LPPY/LPQO of Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa),FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c putative lipoprotein (fragment) from Streptomyces coelicolor (146 aa) [...] | Rv3000, (MTV012.14), len: 219 aa. Possible conserved transmembrane protein, similar to various membrane proteins e.g. P77307|YBBM_ECOLI|B0491 hypothetical 28.2 KDA protein (potential integral membrane protein) from Escherichia coli strain K12 (259 aa), FASTA scores: opt: 292, E(): 3.1e-11,(30.25% identity in 218 aa overlap); N-terminus of Q9BJF3 putative ABC transporter (fragment) from Sterkiella histriomuscorum (1319 aa), FASTA scores: opt: 274, E(): 1.3e-09, (39.6% identity in 101 aa overlap); Q9C9W0|T23K23.21 putative ABC transporter from Arabidopsis thaliana (Mouse-ear cress) (263 [...] | 0.681 |
lppY | Rv3727 | Rv2999 | Rv3727 | Rv2999, (MTV012.13), len: 321 aa. Probable lppY,conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c putative lipoprotein from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 uncharacterized conserved protein similar to LPPY/LPQO of Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa),FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c putative lipoprotein (fragment) from Streptomyces coelicolor (146 aa) [...] | Rv3727, (MTV025.075), len: 602 aa. Possible oxidoreductase, similar to several plants phytoene dehydrogenases/desaturases e.g. Q9HSE1|CRTI3|VNG0277G phytoene dehydrogenase from Halobacterium sp. strain NRC-1 (541 aa), FASTA scores: opt: 299, E(): 1.1e-10, (29.85% identity in 576 aa overlap); Q9FZL6|CITPDS1 phytoene desaturase from Citrus unshiu (Satsuma orange) (553 aa),FASTA scores: opt: 164, E(): 0.018, (24.2% identity in 434 aa overlap); Q07356|CRTI_ARATH|PDS|AT4G14210|DL3145c phytoene dehydrogenase precursor from Arabidopsis thaliana (Mouse-ear cress) (566 aa), FASTA scores: opt: 1 [...] | 0.402 |