node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0990c | Rv3655c | Rv0990c | Rv3655c | Hypothetical protein; Rv0990c, (MTCI237.04c), len: 218 aa. Hypothetical unknown protein. | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Interferes with caspase-8 activation and binds to the host E3 ubiquitin-protein ligase RNF213, whose fusion partners have anti-apoptotic function. | 0.751 |
Rv0990c | Rv3657c | Rv0990c | Rv3657c | Hypothetical protein; Rv0990c, (MTCI237.04c), len: 218 aa. Hypothetical unknown protein. | Rv3657c, (MTV025.005c), len: 191 aa. Possible conserved membrane protein, rich in ala residues, similar to Q9X919|SCH5.17c putative integral membrane protein from Streptomyces coelicolor (267 aa), FASTA scores: opt: 324,E(): 4.7e-12, (40.9% identity in 154 aa overlap). | 0.844 |
Rv0990c | Rv3658c | Rv0990c | Rv3658c | Hypothetical protein; Rv0990c, (MTCI237.04c), len: 218 aa. Hypothetical unknown protein. | Rv3658c, (MTV025.006c), len: 266 aa. Probable conserved transmembrane protein, similar to Q9X920|SCH5.18c putative integral membrane protein from Streptomyces coelicolor (321 aa), FASTA scores: opt: 335, E(): 4.1e-13,(38.05% identity in 247 aa overlap). | 0.812 |
Rv0990c | Rv3659c | Rv0990c | Rv3659c | Hypothetical protein; Rv0990c, (MTCI237.04c), len: 218 aa. Hypothetical unknown protein. | Rv3659c, (MTV025.007c), len: 352 aa. Conserved hypothetical protein, highly similar, but always shorter (various lengths) at N-terminus, to Q9X921|SCH5.19c putative secretory protein from Streptomyces coelicolor (523 aa), FASTA scores: opt: 1287, E(): 5.3e-66, (59.85% identity in 351 aa overlap); Q9HW98|PA4302 probable type II secretion system protein from Pseudomonas aeruginosa (421 aa), FASTA scores: opt: 776, E(): 5.4e-37, (42.8% identity in 320 aa overlap); AAK65510|CPAF2 probable CPAF2 PILUS assembly protein from Rhizobium meliloti (Sinorhizobium meliloti) plasmid pSymA (497 aa) F [...] | 0.576 |
Rv0990c | Rv3660c | Rv0990c | Rv3660c | Hypothetical protein; Rv0990c, (MTCI237.04c), len: 218 aa. Hypothetical unknown protein. | Conserved hypothetical protein; May play a role in septum formation. | 0.754 |
Rv1708 | Rv3660c | Rv1708 | Rv3660c | Putative initiation inhibitor protein; May play a role in septum formation. | Conserved hypothetical protein; May play a role in septum formation. | 0.838 |
Rv2862c | Rv3660c | Rv2862c | Rv3660c | Rv2862c, (MTV003.08), len: 194 aa. Conserved hypothetical protein, showing some similarity with others e.g. Q9X8X5|SCH35.31c hypothetical 19.6 KDA protein from Streptomyces coelicolor (180 aa), FASTA scores: opt: 266,E(): 2.2e-11, (34.65% identity in 179 aa overlap); Q9Z5H1|ML0169|MLCB373.19 hypothetical 22.1 KDA protein from Mycobacterium leprae (200 aa), FASTA scores: opt: 195, E(): 2.3e-06, (30.15% identity in 189 aa overlap); etc. Also some similarity to P71544|Y966_MYCTU|Rv0966c|MT0994|MTCY10D7.08 conserved hypothetical protein from Mycobacterium tuberculosis (230 aa), FASTA score [...] | Conserved hypothetical protein; May play a role in septum formation. | 0.539 |
Rv3654c | Rv3655c | Rv3654c | Rv3655c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Recognizes the host polypyrimidine tract binding protein-associated splicing factor (PSF), which probably leads to its cleavage, diminishing the level of caspase-8 in macrophages. | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Interferes with caspase-8 activation and binds to the host E3 ubiquitin-protein ligase RNF213, whose fusion partners have anti-apoptotic function. | 0.886 |
Rv3654c | Rv3656c | Rv3654c | Rv3656c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Recognizes the host polypyrimidine tract binding protein-associated splicing factor (PSF), which probably leads to its cleavage, diminishing the level of caspase-8 in macrophages. | Rv3656c, (MTV025.004c), len: 68 aa. Conserved hypothetical protein, similar to Q9X918|SCH5.16c small hypothetical protein from Streptomyces coelicolor (75 aa),FASTA scores: opt: 129, E(): 0.0039, (40.0% identity in 60 aa overlap). Equivalent to AAK48120 from Mycobacterium tuberculosis strain CDC1551 (42 aa) but longer 26 aa. | 0.968 |
Rv3654c | Rv3657c | Rv3654c | Rv3657c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Recognizes the host polypyrimidine tract binding protein-associated splicing factor (PSF), which probably leads to its cleavage, diminishing the level of caspase-8 in macrophages. | Rv3657c, (MTV025.005c), len: 191 aa. Possible conserved membrane protein, rich in ala residues, similar to Q9X919|SCH5.17c putative integral membrane protein from Streptomyces coelicolor (267 aa), FASTA scores: opt: 324,E(): 4.7e-12, (40.9% identity in 154 aa overlap). | 0.962 |
Rv3654c | Rv3658c | Rv3654c | Rv3658c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Recognizes the host polypyrimidine tract binding protein-associated splicing factor (PSF), which probably leads to its cleavage, diminishing the level of caspase-8 in macrophages. | Rv3658c, (MTV025.006c), len: 266 aa. Probable conserved transmembrane protein, similar to Q9X920|SCH5.18c putative integral membrane protein from Streptomyces coelicolor (321 aa), FASTA scores: opt: 335, E(): 4.1e-13,(38.05% identity in 247 aa overlap). | 0.827 |
Rv3654c | Rv3659c | Rv3654c | Rv3659c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Recognizes the host polypyrimidine tract binding protein-associated splicing factor (PSF), which probably leads to its cleavage, diminishing the level of caspase-8 in macrophages. | Rv3659c, (MTV025.007c), len: 352 aa. Conserved hypothetical protein, highly similar, but always shorter (various lengths) at N-terminus, to Q9X921|SCH5.19c putative secretory protein from Streptomyces coelicolor (523 aa), FASTA scores: opt: 1287, E(): 5.3e-66, (59.85% identity in 351 aa overlap); Q9HW98|PA4302 probable type II secretion system protein from Pseudomonas aeruginosa (421 aa), FASTA scores: opt: 776, E(): 5.4e-37, (42.8% identity in 320 aa overlap); AAK65510|CPAF2 probable CPAF2 PILUS assembly protein from Rhizobium meliloti (Sinorhizobium meliloti) plasmid pSymA (497 aa) F [...] | 0.964 |
Rv3654c | Rv3660c | Rv3654c | Rv3660c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Recognizes the host polypyrimidine tract binding protein-associated splicing factor (PSF), which probably leads to its cleavage, diminishing the level of caspase-8 in macrophages. | Conserved hypothetical protein; May play a role in septum formation. | 0.858 |
Rv3655c | Rv0990c | Rv3655c | Rv0990c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Interferes with caspase-8 activation and binds to the host E3 ubiquitin-protein ligase RNF213, whose fusion partners have anti-apoptotic function. | Hypothetical protein; Rv0990c, (MTCI237.04c), len: 218 aa. Hypothetical unknown protein. | 0.751 |
Rv3655c | Rv3654c | Rv3655c | Rv3654c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Interferes with caspase-8 activation and binds to the host E3 ubiquitin-protein ligase RNF213, whose fusion partners have anti-apoptotic function. | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Recognizes the host polypyrimidine tract binding protein-associated splicing factor (PSF), which probably leads to its cleavage, diminishing the level of caspase-8 in macrophages. | 0.886 |
Rv3655c | Rv3656c | Rv3655c | Rv3656c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Interferes with caspase-8 activation and binds to the host E3 ubiquitin-protein ligase RNF213, whose fusion partners have anti-apoptotic function. | Rv3656c, (MTV025.004c), len: 68 aa. Conserved hypothetical protein, similar to Q9X918|SCH5.16c small hypothetical protein from Streptomyces coelicolor (75 aa),FASTA scores: opt: 129, E(): 0.0039, (40.0% identity in 60 aa overlap). Equivalent to AAK48120 from Mycobacterium tuberculosis strain CDC1551 (42 aa) but longer 26 aa. | 0.900 |
Rv3655c | Rv3657c | Rv3655c | Rv3657c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Interferes with caspase-8 activation and binds to the host E3 ubiquitin-protein ligase RNF213, whose fusion partners have anti-apoptotic function. | Rv3657c, (MTV025.005c), len: 191 aa. Possible conserved membrane protein, rich in ala residues, similar to Q9X919|SCH5.17c putative integral membrane protein from Streptomyces coelicolor (267 aa), FASTA scores: opt: 324,E(): 4.7e-12, (40.9% identity in 154 aa overlap). | 0.889 |
Rv3655c | Rv3658c | Rv3655c | Rv3658c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Interferes with caspase-8 activation and binds to the host E3 ubiquitin-protein ligase RNF213, whose fusion partners have anti-apoptotic function. | Rv3658c, (MTV025.006c), len: 266 aa. Probable conserved transmembrane protein, similar to Q9X920|SCH5.18c putative integral membrane protein from Streptomyces coelicolor (321 aa), FASTA scores: opt: 335, E(): 4.1e-13,(38.05% identity in 247 aa overlap). | 0.921 |
Rv3655c | Rv3659c | Rv3655c | Rv3659c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Interferes with caspase-8 activation and binds to the host E3 ubiquitin-protein ligase RNF213, whose fusion partners have anti-apoptotic function. | Rv3659c, (MTV025.007c), len: 352 aa. Conserved hypothetical protein, highly similar, but always shorter (various lengths) at N-terminus, to Q9X921|SCH5.19c putative secretory protein from Streptomyces coelicolor (523 aa), FASTA scores: opt: 1287, E(): 5.3e-66, (59.85% identity in 351 aa overlap); Q9HW98|PA4302 probable type II secretion system protein from Pseudomonas aeruginosa (421 aa), FASTA scores: opt: 776, E(): 5.4e-37, (42.8% identity in 320 aa overlap); AAK65510|CPAF2 probable CPAF2 PILUS assembly protein from Rhizobium meliloti (Sinorhizobium meliloti) plasmid pSymA (497 aa) F [...] | 0.903 |
Rv3655c | Rv3660c | Rv3655c | Rv3660c | Conserved hypothetical protein; Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Interferes with caspase-8 activation and binds to the host E3 ubiquitin-protein ligase RNF213, whose fusion partners have anti-apoptotic function. | Conserved hypothetical protein; May play a role in septum formation. | 0.540 |