node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0063 | Rv3096 | Rv0063 | Rv3096 | Rv0063, (MTV030.06), len: 479 aa. Possible oxidoreductase, similar to many. Similar to Mycobacterium tuberculosis proteins e.g. Rv3107c, Rv1257c, etc. Contains PS00862 Oxygen oxidoreductases covalent FAD-binding site. | Rv3096, (MTCY164.07), len: 379 aa. Hypothetical protein, with slight similarity to several proteins e.g. Q09671|OYEB_SCHPO|SPAC5H10.10 putative NADPH dehydrogenase C5H10.10 (old yellow enzyme homolog) from Schizosaccharomyces pombe (Fission yeast) (392 aa), FASTA scores: opt: 125, E(): 1.1, (25.45% identity in 165 aa overlap); and Q12603|XYNA_DICTH beta-1,4-xylanase (endo-1,4-beta-xylanase) from Dictyoglomus thermophilum (352 aa), FASTA scores: opt: 124, E(): 1.2, (25.65% identity in 195 aa overlap); etc. Contains glycosyl hydrolases family 5 signature (PS00659). Predicted to be an out [...] | 0.730 |
Rv0063 | Rv3209 | Rv0063 | Rv3209 | Rv0063, (MTV030.06), len: 479 aa. Possible oxidoreductase, similar to many. Similar to Mycobacterium tuberculosis proteins e.g. Rv3107c, Rv1257c, etc. Contains PS00862 Oxygen oxidoreductases covalent FAD-binding site. | Rv3209, (MTCY07D11.17c), len: 186 aa. Conserved hypothetical thr-, pro-rich protein, equivalent (but shorter 36 aa in N-terminus) to Q9CCH2|ML0813 putative membrane protein from Mycobacterium leprae (195 aa), FASTA scores: opt: 508, E(): 1.4e-15, (58.4% identity in 185 aa overlap). Also some similarity with Q10390|MMS3_MYCTU|MMPS3|Rv2198c|MT2254|MTCY190.09c probable conserved transmembrane transport protein from M. tuberculosis (299 aa), FASTA scores: opt: 339, E(): 3.7e-08, (35.0% identity in 180 aa overlap); and Q9CCE9|MMPS3|ML0877 putative membrane protein from Mycobacterium leprae [...] | 0.716 |
Rv0063 | Rv3717 | Rv0063 | Rv3717 | Rv0063, (MTV030.06), len: 479 aa. Possible oxidoreductase, similar to many. Similar to Mycobacterium tuberculosis proteins e.g. Rv3107c, Rv1257c, etc. Contains PS00862 Oxygen oxidoreductases covalent FAD-binding site. | Conserved hypothetical protein; Cell-wall hydrolase that hydrolyzes the amide bond between N- acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to hydrolyze the cell walls of several bacterial species (i.e. Paenibacillus sp., B.avium, E.coli DH5alpha, E.aerogenes, L.acidophilus, B.thuringiensis, B.pumilus, B.subtilis and E.coli W3110), thereby showing that it is a cell-wall hydrolase with broad-spectrum activity. May have a role in peptidoglycan fragment recycling. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 0.837 |
Rv0063 | ftsW | Rv0063 | Rv2154c | Rv0063, (MTV030.06), len: 479 aa. Possible oxidoreductase, similar to many. Similar to Mycobacterium tuberculosis proteins e.g. Rv3107c, Rv1257c, etc. Contains PS00862 Oxygen oxidoreductases covalent FAD-binding site. | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.533 |
Rv3096 | Rv0063 | Rv3096 | Rv0063 | Rv3096, (MTCY164.07), len: 379 aa. Hypothetical protein, with slight similarity to several proteins e.g. Q09671|OYEB_SCHPO|SPAC5H10.10 putative NADPH dehydrogenase C5H10.10 (old yellow enzyme homolog) from Schizosaccharomyces pombe (Fission yeast) (392 aa), FASTA scores: opt: 125, E(): 1.1, (25.45% identity in 165 aa overlap); and Q12603|XYNA_DICTH beta-1,4-xylanase (endo-1,4-beta-xylanase) from Dictyoglomus thermophilum (352 aa), FASTA scores: opt: 124, E(): 1.2, (25.65% identity in 195 aa overlap); etc. Contains glycosyl hydrolases family 5 signature (PS00659). Predicted to be an out [...] | Rv0063, (MTV030.06), len: 479 aa. Possible oxidoreductase, similar to many. Similar to Mycobacterium tuberculosis proteins e.g. Rv3107c, Rv1257c, etc. Contains PS00862 Oxygen oxidoreductases covalent FAD-binding site. | 0.730 |
Rv3096 | Rv3209 | Rv3096 | Rv3209 | Rv3096, (MTCY164.07), len: 379 aa. Hypothetical protein, with slight similarity to several proteins e.g. Q09671|OYEB_SCHPO|SPAC5H10.10 putative NADPH dehydrogenase C5H10.10 (old yellow enzyme homolog) from Schizosaccharomyces pombe (Fission yeast) (392 aa), FASTA scores: opt: 125, E(): 1.1, (25.45% identity in 165 aa overlap); and Q12603|XYNA_DICTH beta-1,4-xylanase (endo-1,4-beta-xylanase) from Dictyoglomus thermophilum (352 aa), FASTA scores: opt: 124, E(): 1.2, (25.65% identity in 195 aa overlap); etc. Contains glycosyl hydrolases family 5 signature (PS00659). Predicted to be an out [...] | Rv3209, (MTCY07D11.17c), len: 186 aa. Conserved hypothetical thr-, pro-rich protein, equivalent (but shorter 36 aa in N-terminus) to Q9CCH2|ML0813 putative membrane protein from Mycobacterium leprae (195 aa), FASTA scores: opt: 508, E(): 1.4e-15, (58.4% identity in 185 aa overlap). Also some similarity with Q10390|MMS3_MYCTU|MMPS3|Rv2198c|MT2254|MTCY190.09c probable conserved transmembrane transport protein from M. tuberculosis (299 aa), FASTA scores: opt: 339, E(): 3.7e-08, (35.0% identity in 180 aa overlap); and Q9CCE9|MMPS3|ML0877 putative membrane protein from Mycobacterium leprae [...] | 0.730 |
Rv3096 | Rv3717 | Rv3096 | Rv3717 | Rv3096, (MTCY164.07), len: 379 aa. Hypothetical protein, with slight similarity to several proteins e.g. Q09671|OYEB_SCHPO|SPAC5H10.10 putative NADPH dehydrogenase C5H10.10 (old yellow enzyme homolog) from Schizosaccharomyces pombe (Fission yeast) (392 aa), FASTA scores: opt: 125, E(): 1.1, (25.45% identity in 165 aa overlap); and Q12603|XYNA_DICTH beta-1,4-xylanase (endo-1,4-beta-xylanase) from Dictyoglomus thermophilum (352 aa), FASTA scores: opt: 124, E(): 1.2, (25.65% identity in 195 aa overlap); etc. Contains glycosyl hydrolases family 5 signature (PS00659). Predicted to be an out [...] | Conserved hypothetical protein; Cell-wall hydrolase that hydrolyzes the amide bond between N- acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to hydrolyze the cell walls of several bacterial species (i.e. Paenibacillus sp., B.avium, E.coli DH5alpha, E.aerogenes, L.acidophilus, B.thuringiensis, B.pumilus, B.subtilis and E.coli W3110), thereby showing that it is a cell-wall hydrolase with broad-spectrum activity. May have a role in peptidoglycan fragment recycling. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 0.797 |
Rv3209 | Rv0063 | Rv3209 | Rv0063 | Rv3209, (MTCY07D11.17c), len: 186 aa. Conserved hypothetical thr-, pro-rich protein, equivalent (but shorter 36 aa in N-terminus) to Q9CCH2|ML0813 putative membrane protein from Mycobacterium leprae (195 aa), FASTA scores: opt: 508, E(): 1.4e-15, (58.4% identity in 185 aa overlap). Also some similarity with Q10390|MMS3_MYCTU|MMPS3|Rv2198c|MT2254|MTCY190.09c probable conserved transmembrane transport protein from M. tuberculosis (299 aa), FASTA scores: opt: 339, E(): 3.7e-08, (35.0% identity in 180 aa overlap); and Q9CCE9|MMPS3|ML0877 putative membrane protein from Mycobacterium leprae [...] | Rv0063, (MTV030.06), len: 479 aa. Possible oxidoreductase, similar to many. Similar to Mycobacterium tuberculosis proteins e.g. Rv3107c, Rv1257c, etc. Contains PS00862 Oxygen oxidoreductases covalent FAD-binding site. | 0.716 |
Rv3209 | Rv3096 | Rv3209 | Rv3096 | Rv3209, (MTCY07D11.17c), len: 186 aa. Conserved hypothetical thr-, pro-rich protein, equivalent (but shorter 36 aa in N-terminus) to Q9CCH2|ML0813 putative membrane protein from Mycobacterium leprae (195 aa), FASTA scores: opt: 508, E(): 1.4e-15, (58.4% identity in 185 aa overlap). Also some similarity with Q10390|MMS3_MYCTU|MMPS3|Rv2198c|MT2254|MTCY190.09c probable conserved transmembrane transport protein from M. tuberculosis (299 aa), FASTA scores: opt: 339, E(): 3.7e-08, (35.0% identity in 180 aa overlap); and Q9CCE9|MMPS3|ML0877 putative membrane protein from Mycobacterium leprae [...] | Rv3096, (MTCY164.07), len: 379 aa. Hypothetical protein, with slight similarity to several proteins e.g. Q09671|OYEB_SCHPO|SPAC5H10.10 putative NADPH dehydrogenase C5H10.10 (old yellow enzyme homolog) from Schizosaccharomyces pombe (Fission yeast) (392 aa), FASTA scores: opt: 125, E(): 1.1, (25.45% identity in 165 aa overlap); and Q12603|XYNA_DICTH beta-1,4-xylanase (endo-1,4-beta-xylanase) from Dictyoglomus thermophilum (352 aa), FASTA scores: opt: 124, E(): 1.2, (25.65% identity in 195 aa overlap); etc. Contains glycosyl hydrolases family 5 signature (PS00659). Predicted to be an out [...] | 0.730 |
Rv3209 | Rv3717 | Rv3209 | Rv3717 | Rv3209, (MTCY07D11.17c), len: 186 aa. Conserved hypothetical thr-, pro-rich protein, equivalent (but shorter 36 aa in N-terminus) to Q9CCH2|ML0813 putative membrane protein from Mycobacterium leprae (195 aa), FASTA scores: opt: 508, E(): 1.4e-15, (58.4% identity in 185 aa overlap). Also some similarity with Q10390|MMS3_MYCTU|MMPS3|Rv2198c|MT2254|MTCY190.09c probable conserved transmembrane transport protein from M. tuberculosis (299 aa), FASTA scores: opt: 339, E(): 3.7e-08, (35.0% identity in 180 aa overlap); and Q9CCE9|MMPS3|ML0877 putative membrane protein from Mycobacterium leprae [...] | Conserved hypothetical protein; Cell-wall hydrolase that hydrolyzes the amide bond between N- acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to hydrolyze the cell walls of several bacterial species (i.e. Paenibacillus sp., B.avium, E.coli DH5alpha, E.aerogenes, L.acidophilus, B.thuringiensis, B.pumilus, B.subtilis and E.coli W3110), thereby showing that it is a cell-wall hydrolase with broad-spectrum activity. May have a role in peptidoglycan fragment recycling. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 0.804 |
Rv3209 | ftsW | Rv3209 | Rv2154c | Rv3209, (MTCY07D11.17c), len: 186 aa. Conserved hypothetical thr-, pro-rich protein, equivalent (but shorter 36 aa in N-terminus) to Q9CCH2|ML0813 putative membrane protein from Mycobacterium leprae (195 aa), FASTA scores: opt: 508, E(): 1.4e-15, (58.4% identity in 185 aa overlap). Also some similarity with Q10390|MMS3_MYCTU|MMPS3|Rv2198c|MT2254|MTCY190.09c probable conserved transmembrane transport protein from M. tuberculosis (299 aa), FASTA scores: opt: 339, E(): 3.7e-08, (35.0% identity in 180 aa overlap); and Q9CCE9|MMPS3|ML0877 putative membrane protein from Mycobacterium leprae [...] | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.793 |
Rv3594 | Rv3717 | Rv3594 | Rv3717 | Rv3594, (MTCY07H7B.28c), len: 275 aa. Hypothetical protein, highly similar in part with Q9ZX49|GP29 from Mycobacteriophage TM4 (547 aa), FASTA scores: opt: 526,E(): 1.3e-25, (46.25% identity in 186 aa overlap); and Q9FZS0|LYSA|GP2 from Mycobacterium phage Ms6 (384 aa) FASTA scores: opt: 147, E(): 0.064, (33.35% identity in 84 aa overlap). | Conserved hypothetical protein; Cell-wall hydrolase that hydrolyzes the amide bond between N- acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to hydrolyze the cell walls of several bacterial species (i.e. Paenibacillus sp., B.avium, E.coli DH5alpha, E.aerogenes, L.acidophilus, B.thuringiensis, B.pumilus, B.subtilis and E.coli W3110), thereby showing that it is a cell-wall hydrolase with broad-spectrum activity. May have a role in peptidoglycan fragment recycling. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 0.909 |
Rv3594 | Rv3811 | Rv3594 | Rv3811 | Rv3594, (MTCY07H7B.28c), len: 275 aa. Hypothetical protein, highly similar in part with Q9ZX49|GP29 from Mycobacteriophage TM4 (547 aa), FASTA scores: opt: 526,E(): 1.3e-25, (46.25% identity in 186 aa overlap); and Q9FZS0|LYSA|GP2 from Mycobacterium phage Ms6 (384 aa) FASTA scores: opt: 147, E(): 0.064, (33.35% identity in 84 aa overlap). | Rv3811, (MTV026.16), len: 539 aa. Conserved hypothetical protein, showing some similarity to Q9KZK5|SCE34.21c putative secreted protein from Streptomyces coelicolor (416 aa), FASTA scores: opt: 603,E(): 8.1e-26, (34.4% identity in 404 aa overlap); Q9S2P9|SC5F7.14c hypothetical 31.9 KDA protein from Streptomyces coelicolor (308 aa), FASTA scores: opt: 472,E(): 9.5e-19, (37.5% identity in 208 aa overlap). Middle section (approximately aa 185-350/390) shows some similarity with Q9GK12 peptidoglycan recognition protein precursor from Camelus dromedarius (Dromedary) (Arabian camel) (193 aa) [...] | 0.920 |
Rv3594 | cwlM | Rv3594 | Rv3915 | Rv3594, (MTCY07H7B.28c), len: 275 aa. Hypothetical protein, highly similar in part with Q9ZX49|GP29 from Mycobacteriophage TM4 (547 aa), FASTA scores: opt: 526,E(): 1.3e-25, (46.25% identity in 186 aa overlap); and Q9FZS0|LYSA|GP2 from Mycobacterium phage Ms6 (384 aa) FASTA scores: opt: 147, E(): 0.064, (33.35% identity in 84 aa overlap). | Probable peptidoglycan hydrolase; Cell-wall hydrolase that hydrolyzes the amide bond between N- acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to lyse whole mycobacteria, release peptidoglycan from the cell wall of M.luteus and M.smegmatis, and cleave N-acetylmuramoyl-L-alanyl-D- isoglutamine, releasing free N-acetylmuramic acid and dipeptide. | 0.912 |
Rv3594 | ripA | Rv3594 | Rv1477 | Rv3594, (MTCY07H7B.28c), len: 275 aa. Hypothetical protein, highly similar in part with Q9ZX49|GP29 from Mycobacteriophage TM4 (547 aa), FASTA scores: opt: 526,E(): 1.3e-25, (46.25% identity in 186 aa overlap); and Q9FZS0|LYSA|GP2 from Mycobacterium phage Ms6 (384 aa) FASTA scores: opt: 147, E(): 0.064, (33.35% identity in 84 aa overlap). | Peptidoglycan hydrolase; Peptidoglycan endopeptidase that cleaves the bond between D- glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan from a number of Actinobacteria; activity is increased in the presence of RpfB and inhibited by PBP1A (ponA1). Required for normal separation of daughter cells after cell division and for cell wall integrity. Required for host cell invasion and intracellular survival in host macrophages. Belongs to the peptidase C40 family. | 0.576 |
Rv3716c | Rv3717 | Rv3716c | Rv3717 | Conserved protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Conserved hypothetical protein; Cell-wall hydrolase that hydrolyzes the amide bond between N- acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to hydrolyze the cell walls of several bacterial species (i.e. Paenibacillus sp., B.avium, E.coli DH5alpha, E.aerogenes, L.acidophilus, B.thuringiensis, B.pumilus, B.subtilis and E.coli W3110), thereby showing that it is a cell-wall hydrolase with broad-spectrum activity. May have a role in peptidoglycan fragment recycling. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | 0.776 |
Rv3716c | recR | Rv3716c | Rv3715c | Conserved protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Probable recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.983 |
Rv3717 | Rv0063 | Rv3717 | Rv0063 | Conserved hypothetical protein; Cell-wall hydrolase that hydrolyzes the amide bond between N- acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to hydrolyze the cell walls of several bacterial species (i.e. Paenibacillus sp., B.avium, E.coli DH5alpha, E.aerogenes, L.acidophilus, B.thuringiensis, B.pumilus, B.subtilis and E.coli W3110), thereby showing that it is a cell-wall hydrolase with broad-spectrum activity. May have a role in peptidoglycan fragment recycling. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | Rv0063, (MTV030.06), len: 479 aa. Possible oxidoreductase, similar to many. Similar to Mycobacterium tuberculosis proteins e.g. Rv3107c, Rv1257c, etc. Contains PS00862 Oxygen oxidoreductases covalent FAD-binding site. | 0.837 |
Rv3717 | Rv3096 | Rv3717 | Rv3096 | Conserved hypothetical protein; Cell-wall hydrolase that hydrolyzes the amide bond between N- acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to hydrolyze the cell walls of several bacterial species (i.e. Paenibacillus sp., B.avium, E.coli DH5alpha, E.aerogenes, L.acidophilus, B.thuringiensis, B.pumilus, B.subtilis and E.coli W3110), thereby showing that it is a cell-wall hydrolase with broad-spectrum activity. May have a role in peptidoglycan fragment recycling. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | Rv3096, (MTCY164.07), len: 379 aa. Hypothetical protein, with slight similarity to several proteins e.g. Q09671|OYEB_SCHPO|SPAC5H10.10 putative NADPH dehydrogenase C5H10.10 (old yellow enzyme homolog) from Schizosaccharomyces pombe (Fission yeast) (392 aa), FASTA scores: opt: 125, E(): 1.1, (25.45% identity in 165 aa overlap); and Q12603|XYNA_DICTH beta-1,4-xylanase (endo-1,4-beta-xylanase) from Dictyoglomus thermophilum (352 aa), FASTA scores: opt: 124, E(): 1.2, (25.65% identity in 195 aa overlap); etc. Contains glycosyl hydrolases family 5 signature (PS00659). Predicted to be an out [...] | 0.797 |
Rv3717 | Rv3209 | Rv3717 | Rv3209 | Conserved hypothetical protein; Cell-wall hydrolase that hydrolyzes the amide bond between N- acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to hydrolyze the cell walls of several bacterial species (i.e. Paenibacillus sp., B.avium, E.coli DH5alpha, E.aerogenes, L.acidophilus, B.thuringiensis, B.pumilus, B.subtilis and E.coli W3110), thereby showing that it is a cell-wall hydrolase with broad-spectrum activity. May have a role in peptidoglycan fragment recycling. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. | Rv3209, (MTCY07D11.17c), len: 186 aa. Conserved hypothetical thr-, pro-rich protein, equivalent (but shorter 36 aa in N-terminus) to Q9CCH2|ML0813 putative membrane protein from Mycobacterium leprae (195 aa), FASTA scores: opt: 508, E(): 1.4e-15, (58.4% identity in 185 aa overlap). Also some similarity with Q10390|MMS3_MYCTU|MMPS3|Rv2198c|MT2254|MTCY190.09c probable conserved transmembrane transport protein from M. tuberculosis (299 aa), FASTA scores: opt: 339, E(): 3.7e-08, (35.0% identity in 180 aa overlap); and Q9CCE9|MMPS3|ML0877 putative membrane protein from Mycobacterium leprae [...] | 0.804 |