STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icdIsocitrate dehydrogenase; silverDB:HdN1F2078. (419 aa)    
Predicted Functional Partners:
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.990
acnB
Aconitate hydratase 2; silverDB:HdN1F2175; Belongs to the aconitase/IPM isomerase family.
  
 
 0.981
sucA
2-oxoglutarate dehydrogenase, E1 subunit; silverDB:HdN1F2068.
   
 
 0.966
korA
2-ketoglutarate: nadp oxidoreductase, alpha subunit; silverDB:HdN1F1254.
  
 
 0.940
gdhA
Glutamate/leucine/phenylalanine/valine dehydrogenase; silverDB:HdN1F1222; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.934
CBL46852.1
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.923
korB
2-ketoglutarate: NADP oxidoreductase, beta subunit; silverDB:HdN1F1255.
     
 0.915
glsI
Ferredoxin-dependent glutamate synthase; silverDB:HdN1F4117.
    
 0.911
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.905
CBL45622.1
Isocitrate/isopropylmalate dehydrogenase family protein; silverDB:HdN1F2685.
     
  0.900
Your Current Organism:
gamma proteobacterium HdN1
NCBI taxonomy Id: 83406
Other names: g. proteobacterium HdN1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.