node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A1L8GQN9 | A0A1L8H4Q1 | A0A1L8GQN9 | A0A1L8H4Q1 | Protein kinase domain-containing protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.934 |
A0A1L8GQN9 | Tp53.L | A0A1L8GQN9 | A0A1L8H4M6 | Protein kinase domain-containing protein. | P53 domain-containing protein. | 0.993 |
A0A1L8GQN9 | pin1 | A0A1L8GQN9 | Q6DEE1 | Protein kinase domain-containing protein. | Peptidyl-prolyl cis-trans isomerase. | 0.783 |
A0A1L8GQN9 | pin1-2 | A0A1L8GQN9 | Q9I9K6 | Protein kinase domain-containing protein. | Peptidyl-prolyl cis-trans isomerase. | 0.783 |
A0A1L8GQN9 | pin4 | A0A1L8GQN9 | A0A1L8F6N9 | Protein kinase domain-containing protein. | Peptidyl-prolyl cis-trans isomerase. | 0.406 |
A0A1L8H4Q1 | A0A1L8GQN9 | A0A1L8H4Q1 | A0A1L8GQN9 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Protein kinase domain-containing protein. | 0.934 |
A0A1L8H4Q1 | pin1 | A0A1L8H4Q1 | Q6DEE1 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Peptidyl-prolyl cis-trans isomerase. | 0.796 |
A0A1L8H4Q1 | pin1-2 | A0A1L8H4Q1 | Q9I9K6 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Peptidyl-prolyl cis-trans isomerase. | 0.796 |
A0A1L8H4Q1 | pin4 | A0A1L8H4Q1 | A0A1L8F6N9 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Peptidyl-prolyl cis-trans isomerase. | 0.411 |
Irf3.L | Tp53.L | A0A1L8FNA8 | A0A1L8H4M6 | IRF tryptophan pentad repeat domain-containing protein. | P53 domain-containing protein. | 0.447 |
Irf3.L | irf3 | A0A1L8FNA8 | A0A1L8FGY4 | IRF tryptophan pentad repeat domain-containing protein. | IRF tryptophan pentad repeat domain-containing protein. | 0.900 |
Irf3.L | pin1 | A0A1L8FNA8 | Q6DEE1 | IRF tryptophan pentad repeat domain-containing protein. | Peptidyl-prolyl cis-trans isomerase. | 0.967 |
Irf3.L | pin1-2 | A0A1L8FNA8 | Q9I9K6 | IRF tryptophan pentad repeat domain-containing protein. | Peptidyl-prolyl cis-trans isomerase. | 0.967 |
Tp53.L | A0A1L8GQN9 | A0A1L8H4M6 | A0A1L8GQN9 | P53 domain-containing protein. | Protein kinase domain-containing protein. | 0.993 |
Tp53.L | Irf3.L | A0A1L8H4M6 | A0A1L8FNA8 | P53 domain-containing protein. | IRF tryptophan pentad repeat domain-containing protein. | 0.447 |
Tp53.L | Wee1.S | A0A1L8H4M6 | A0A1L8GDX5 | P53 domain-containing protein. | Wee1-like protein kinase. | 0.578 |
Tp53.L | Wee2 | A0A1L8H4M6 | A0A1L8GQG4 | P53 domain-containing protein. | Wee1-like protein kinase. | 0.579 |
Tp53.L | irf3 | A0A1L8H4M6 | A0A1L8FGY4 | P53 domain-containing protein. | IRF tryptophan pentad repeat domain-containing protein. | 0.447 |
Tp53.L | pin1 | A0A1L8H4M6 | Q6DEE1 | P53 domain-containing protein. | Peptidyl-prolyl cis-trans isomerase. | 0.791 |
Tp53.L | pin1-2 | A0A1L8H4M6 | Q9I9K6 | P53 domain-containing protein. | Peptidyl-prolyl cis-trans isomerase. | 0.789 |