STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcsk1Zygote arrest 1; Belongs to the peptidase S8 family. (749 aa)    
Predicted Functional Partners:
bsnd
Distal membrane arm assembly complex 2.
      
 0.700
usp24
Proteasome subunit beta 6; Belongs to the peptidase C19 family.
      
 0.691
MC4R
Melanocortin 4 receptor.
      
 0.574
cpe
Uncharacterized protein.
   
  
 0.573
ripk1
Sequestosome 1.
   
  
 0.544
ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
  
 0.541
nhlh1
Citrate lyase beta like.
      
 0.506
pomc
GDNF family receptor alpha 4.
      
 0.453
MGC145330
Protein phosphatase 1 regulatory subunit 12C.
   
  
 0.421
cartpt
Uncharacterized protein.
   
  
 0.421
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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