STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prdx1Uncharacterized protein; Peroxiredoxin 1 (202 aa)    
Predicted Functional Partners:
trx1
Thioredoxin; MGC80314 protein; Belongs to the thioredoxin family
  
 0.981
sesn2
Uncharacterized protein; Sestrin 2
    
 0.968
sesn3
Sestrin 3
    
 0.941
sesn1
Sesn1 protein; Sestrin 1
    
 0.931
prdx5
Uncharacterized protein; Peroxiredoxin 5
   
 
 0.920
gdpd5
Glycerophosphodiester phosphodiesterase domain containing 5
   
 
 0.897
sod1
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family
   
 
 0.865
txn
Hypothetical LOC496541; Thioredoxin
  
 
 0.795
txnrd1
Thioredoxin reductase 1; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
  
 
 0.736
cat.2
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide
  
 
 0.733
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. (Silurana) tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, Xenopus tropicalis, western clawed frog
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