node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NCAPD2 | SMC5 | ENSXETP00000016627 | ENSXETP00000013223 | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. | Structural maintenance of chromosomes 5. | 0.831 |
NCAPD2 | ncapg | ENSXETP00000016627 | ENSXETP00000010739 | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. | Protein tyrosine phosphatase non-receptor type 9. | 0.989 |
NCAPD2 | ncaph | ENSXETP00000016627 | ENSXETP00000035510 | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. | 0.999 |
NCAPD2 | smc6-2 | ENSXETP00000016627 | ENSXETP00000030034 | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. | Spastin. | 0.711 |
NSMCE4A | SMC5 | ENSXETP00000008201 | ENSXETP00000013223 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | Structural maintenance of chromosomes 5. | 0.996 |
NSMCE4A | mdc1 | ENSXETP00000008201 | ENSXETP00000004309 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | Developmentally regulated GTP binding protein 2. | 0.496 |
NSMCE4A | nsmce1 | ENSXETP00000008201 | ENSXETP00000045167 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | Non-structural maintenance of chromosomes element 1 homolog; RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex. Involved in maintenance of genome integrity, DNA damage response and DNA repair. Belongs to the NSE1 family. | 0.996 |
NSMCE4A | nsmce2 | ENSXETP00000008201 | ENSXETP00000053994 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | Ring finger protein 34, E3 ubiquitin protein ligase. | 0.978 |
NSMCE4A | paxip1 | ENSXETP00000008201 | ENSXETP00000041000 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | Ribosomal protein lateral stalk subunit P2. | 0.496 |
NSMCE4A | smc6-2 | ENSXETP00000008201 | ENSXETP00000030034 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | Spastin. | 0.836 |
NSMCE4A | tpt1-2 | ENSXETP00000008201 | ENSXETP00000034911 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | Translationally-controlled tumor protein homolog. | 0.921 |
SMC5 | NCAPD2 | ENSXETP00000013223 | ENSXETP00000016627 | Structural maintenance of chromosomes 5. | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. | 0.831 |
SMC5 | NSMCE4A | ENSXETP00000013223 | ENSXETP00000008201 | Structural maintenance of chromosomes 5. | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | 0.996 |
SMC5 | mdc1 | ENSXETP00000013223 | ENSXETP00000004309 | Structural maintenance of chromosomes 5. | Developmentally regulated GTP binding protein 2. | 0.729 |
SMC5 | ncapg | ENSXETP00000013223 | ENSXETP00000010739 | Structural maintenance of chromosomes 5. | Protein tyrosine phosphatase non-receptor type 9. | 0.800 |
SMC5 | ncaph | ENSXETP00000013223 | ENSXETP00000035510 | Structural maintenance of chromosomes 5. | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. | 0.871 |
SMC5 | nsmce1 | ENSXETP00000013223 | ENSXETP00000045167 | Structural maintenance of chromosomes 5. | Non-structural maintenance of chromosomes element 1 homolog; RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex. Involved in maintenance of genome integrity, DNA damage response and DNA repair. Belongs to the NSE1 family. | 0.996 |
SMC5 | nsmce2 | ENSXETP00000013223 | ENSXETP00000053994 | Structural maintenance of chromosomes 5. | Ring finger protein 34, E3 ubiquitin protein ligase. | 0.996 |
SMC5 | paxip1 | ENSXETP00000013223 | ENSXETP00000041000 | Structural maintenance of chromosomes 5. | Ribosomal protein lateral stalk subunit P2. | 0.729 |
SMC5 | smc6-2 | ENSXETP00000013223 | ENSXETP00000030034 | Structural maintenance of chromosomes 5. | Spastin. | 0.932 |