STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (778 aa)    
Predicted Functional Partners:
PLXND1
Plexin D1.
    
 
 0.789
nrp1
Neuropilin; Belongs to the neuropilin family.
    
 
 0.710
dok4
Downstream of tyrosine kinase 4.
      
 0.599
nrp2
Neuropilin; Belongs to the neuropilin family.
    
 
 0.596
plxna1
Sema domain-containing protein.
    
 
 0.583
plxna2
Plxna2 protein.
    
 
 0.583
plxna4
Ribosomal RNA adenine dimethylase domain-containing 1.
    
 
 0.553
NETO1
Neuropilin and tolloid like 1.
      
 0.550
nfatc4
Nuclear factor of activated T cells 4.
    
 
 0.493
gnrh1
Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family.
      
 0.442
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.