STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bace2-2Purinergic receptor P2X, ligand gated ion channel, 2. (177 aa)    
Predicted Functional Partners:
snx24
PX domain-containing protein.
      
 0.672
tnfrsf9
TNFR-Cys domain-containing protein.
   
 
 0.647
itih5-2
Leucine rich repeat containing 41.
   
  
 0.614
LOC100491070
Uncharacterized protein.
    
 
 0.610
cd40
CD40.
   
  
 0.608
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
      
 0.595
FOXP3
Forkhead box P3.
   
  
 0.564
CD276
CD276 molecule.
   
  
 0.549
cnot3-2
Prenylcysteine oxidase 1.
      
 0.439
traf5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 
 0.436
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.