STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1609 aa)    
Predicted Functional Partners:
eif4e
Sorting nexin 1; Belongs to the eukaryotic initiation factor 4E family.
   
 0.967
eif4a1
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.967
eif4a2
Myb/SANT-like DNA-binding domain-containing protein 4; Belongs to the DEAD box helicase family.
   
 0.967
eif4e1b
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
   
 0.967
eif4e2
Thioredoxin reductase 1; Belongs to the eukaryotic initiation factor 4E family.
    
 0.929
eif4g2
Scaffold attachment factor B.
   
0.926
eif4g3
Uncharacterized protein.
  
 
 
0.925
eif3b
Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.
   
 
 0.799
eif3a
Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
 
 0.745
pabpc1l
Embryonic polyadenylate-binding protein; Binds and protects the poly(A) tail of mRNA with or without an AU-rich element (ARE) and prevents mRNA deadenylation. Stimulates the translation of mRNAs to which it is bound during early development (By similarity).
   
 
 0.740
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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