STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pkn1Uncharacterized protein. (953 aa)    
Predicted Functional Partners:
rhoa.2
Nuclear receptor binding SET domain protein 3.
    
 0.927
rhoa
Ras homolog gene family, member A.
    
 0.927
rhoc
Calponin 3, acidic.
    
 0.927
LOC100493742
Uncharacterized protein; Belongs to the protein kinase superfamily.
  
  
 
0.902
clptm1l-2
CLPTM1-like; Belongs to the protein kinase superfamily.
     
 
0.900
PIGN
Phosphatidylinositol glycan anchor biosynthesis class N.
    
  0.710
sgk1
Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response (By similarity). Plays an important role in activating certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
  
 
0.583
rplp0
60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
   
 
 0.565
prkcg
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
  
 
0.563
ARHGAP12
Rho GTPase activating protein 12.
   
 0.545
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.