STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zbtb48Microtubule affinity regulating kinase 2. (736 aa)    
Predicted Functional Partners:
nol9
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit.
      
 0.607
naif1
Novel protein.
   
  
 0.592
dclre1b
Heat shock protein family A (Hsp70) member 5.
    
 
 0.548
stk11ip
Serine/threonine-protein kinase 11-interacting protein.
   
    0.499
srbd1
Coiled-coil domain-containing protein 69.
    
 
 0.479
HMBOX1
Homeobox containing 1.
      
 0.465
pax3
Paired box protein Pax-3; Probable transcription factor. Promotes both hatching gland and neural crest cell fates, two of the cell populations that arise from the neural plate border. Acts downstream of msx1 to induce the neural crest, cooperating with zic1 and mediating signals from both the wnt and fgf8 signaling pathways. Induction of hatching gland cell fate is independent of zic1 (By similarity); Belongs to the paired homeobox family.
    
 
 0.458
PAX7
Paired box 7.
    
 
 0.458
NR2C2
Nuclear receptor subfamily 2 group C member 2.
    
 
 0.404
nr2c1
Nuclear receptor subfamily 2 group C member 1; Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences (By similarity).
    
 
 0.403
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.