STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
seh1lNucleoporin SEH1; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. Belongs to the WD repeat SEC13 family. (383 aa)    
Predicted Functional Partners:
nprl2
Uncharacterized protein.
   
 0.999
wdr24
Rho/Rac guanine nucleotide exchange factor 18.
    
 0.999
nup107
Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).
   
 0.999
mios
Zinc_ribbon_16 domain-containing protein.
    
 0.999
wdr59
Damage-specific DNA binding protein 1.
    
 0.999
nup85
Nuclear pore complex protein Nup85; Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity). Involved in nephrogenesis ; Belongs to the nucleoporin Nup85 family.
   
 0.999
sec13
SEC13-like 1 (S. cerevisiae); Belongs to the WD repeat SEC13 family.
    
0.999
nup98
Peptidase S59 domain-containing protein.
   
 0.998
NUP133
Nucleoporin 133.
   
 
 0.996
nprl3
Insulin-like growth factor-binding protein complex acid labile subunit-like.
    
 0.991
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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