STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bbs5Bardet-Biedl syndrome 5 protein homolog; Required for ciliogenesis; Belongs to the BBS5 family. (356 aa)    
Predicted Functional Partners:
TTC8
Tetratricopeptide repeat domain 8.
  
 
 0.840
bbs1
Coiled-coil domain containing 84.
    
 
 0.835
bbs9
Adenosine deaminase 2.
   
 
 0.820
pcsk4
Corticotropin releasing hormone receptor 1, gene 2; Belongs to the peptidase S8 family.
    
  0.804
csnk1a1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
  0.801
plcd1
Phosphoinositide phospholipase C.
     
  0.800
bbs7
Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.
   
 
 0.771
bbs2
Bardet-Biedl syndrome 2 protein homolog.
    
 
 0.760
bbs4
Bardet-Biedl syndrome 4 protein homolog; May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome. Required for microtubule anchoring at the centrosome but not for microtubule nucleation. Required for ciliogenesis (By similarity); Belongs to the BBS4 family.
    
 
 0.727
myo18b
Myosin 18b.
    
 0.597
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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