STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
espnUncharacterized protein. (1349 aa)    
Predicted Functional Partners:
MYO3B
Myosin IIIB.
    
 
 0.699
pgghg
Protein-glucosylgalactosylhydroxylysine glucosidase.
    
 
 0.699
WHRN
Whirlin.
    
 
 0.638
lrrc30
Golgin A7.
    
 
 0.597
MATN3
Matrilin 3.
   
  0.571
tada2b
Transcriptional adapter.
    
  0.555
tspear
SET and MYND domain containing 1.
    
 
 0.555
grxcr2
Storkhead box 2.
      
 0.555
tada3
Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context (By similarity); Belongs to the NGG1 family.
   
  0.555
mcm8
DNA helicase MCM8; Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. In eggs, required for elongation during DNA replication by facilitating the recruitment of rpa2/rpa34 and stimulating the processivity of DNA polymerases at replication [...]
    
  0.552
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.