STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
anp32cAcidic leucine-rich nuclear phosphoprotein 32 family member B; Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome (By similarity) (242 aa)    
Predicted Functional Partners:
h2afz
H2A histone family, member Z
   
 
 0.767
dnajb14
DnaJ homolog subfamily B member 14; Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway. Acts by determining hspa8/Hsc70's ATPase and polypeptide-binding activities. Can also act independently of hspa8/Hsc70: together with dnajb12, acts as a chaperone that promotes maturation of potassium channels by stabilizing nascent channel subunits and assembling them into tetramers. While stabilization of nascent channel pro [...]
   
  
 0.712
mttp.1
Microsomal triglyceride transfer protein large subunit; Microsomal triglyceride transfer protein, gene 1
      
 0.680
mttp.2
Microsomal triglyceride transfer protein large subunit; Microsomal triglyceride transfer protein, gene 2
      
 0.680
myo1f
Unconventional myosin-if; Myosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family
   
  
 0.675
bank1
B-cell scaffold protein with ankyrin repeats 1
      
 0.673
dapp1
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; Dual adaptor of phosphotyrosine and 3-phosphoinositides
      
 0.671
SFXN4
Sideroflexin-4 isoform X1; Uncharacterized protein; Sideroflexin 4
      
 0.670
tbcb
Tubulin-specific chaperone b; Tubulin folding cofactor B
   
  
 0.666
dus3l
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs
   
  
 0.649
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. (Silurana) tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, western clawed frog
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