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foxd3 protein (Xenopus tropicalis) - STRING interaction network
"foxd3" - Forkhead box protein D3 in Xenopus tropicalis
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
foxd3Forkhead box protein D3; Transcriptional repressor that is an essential upstream regulator of neural crest determination. Also acts in a negative auto-regulator loop by inhibiting the transcription of its own gene (By similarity) (369 aa)    
Predicted Functional Partners:
sox10
Transcription factor Sox-10; Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox8 and sox9 to induce neural crest progenitors. Acts downstream of wnt-signaling at the neural plate border. Involved in the specification of neural crest progenitors fated to form the pigment cell lineage (By similarity) (436 aa)
     
 
  0.956
tfap2a
Uncharacterized protein; Transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (442 aa)
     
 
  0.900
snai2
Snail homolog 2 (266 aa)
           
  0.893
msx1
Uncharacterized protein; Msh homeobox 1 (297 aa)
       
 
  0.884
zic1
Zic family member 1 (445 aa)
       
 
  0.839
pax3
Paired box protein Pax-3; Probable transcription factor. Promotes both hatching gland and neural crest cell fates, two of the cell populations that arise from the neural plate border. Acts downstream of msx1 to induce the neural crest, cooperating with zic1 and mediating signals from both the wnt and fgf8 signaling pathways. Induction of hatching gland cell fate is independent of zic1 (By similarity) (400 aa)
       
 
  0.838
snai1
Novel similar to snail homolog 2 (Drosophila) (SNAI2); Snail homolog 1 (262 aa)
           
  0.816
mitf
Microphthalmia-associated transcription factor (483 aa)
       
 
  0.816
pax7
Paired box 7 (522 aa)
       
 
  0.810
twist1
Uncharacterized protein; Twist homolog 1 (171 aa)
           
  0.778
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. (Silurana) tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, Xenopus tropicalis, western clawed frog
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