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triap1 protein (Xenopus Silurana) - STRING interaction network
"triap1" - TP53 regulated inhibitor of apoptosis 1 in Xenopus Silurana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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triap1TP53 regulated inhibitor of apoptosis 1; Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. The triap1-prelid1 complex probably functions as a phosphatidic acid (PA) transporter across the mitochondrion intermembrane space to provide PA for cardiolipin CL synthesis in the inner membrane. Likewise, the triap1-prelid3a complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo [...] (78 aa)    
Predicted Functional Partners:
prelid1
PRELI domain containing 1 (216 aa)
     
  0.996
slmo1
Slowmo homolog 1 (172 aa)
       
 
  0.767
ENSXETG00000014908
Trans-2-enoyl-CoA reductase, mitochondrial (333 aa)
           
  0.674
nrbf1
Mitochondrial trans-2-enoyl-CoA reductase; Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2- decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis (By similarity). Functions in pronephros development, regulating late differentiation of all pronephric tubule segments (350 aa)
           
  0.674
tp53
Tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (366 aa)
     
  0.590
aars
alanyl-tRNA synthetase (992 aa)
     
   
  0.566
snrpg
Small nuclear ribonucleoprotein polypeptide G (76 aa)
     
        0.432
polr2j
Polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa (117 aa)
     
   
  0.429
tmem14c
Transmembrane protein 14C (107 aa)
     
   
  0.411
wbscr22
Williams Beuren syndrome chromosome region 22 (282 aa)
     
   
  0.410
Your Current Organism:
Xenopus Silurana
NCBI taxonomy Id: 8364
Other names: Amphibia, Anura, Batrachia, Lissamphibia, Mesobatrachia, Pipidae, Pipoidea, Salientia, Silurana, Silurana tropicalis, Siluraninae, X. (Silurana) tropicalis, Xenopodinae, Xenopus, Xenopus (Silurana) tropicalis, Xenopus Silurana, Xenopus laevis tropicalis, Xenopus tropicalis, Xenopus tropicalis group, amphibians, anurans, frogs, frogs & toads, frogs and toads, pipid frogs, tongueless frogs, western clawed frog
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