STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serinc2-2Nucleoporin NUP188 homolog. (683 aa)    
Predicted Functional Partners:
gak
Uncharacterized protein.
   
 
 0.877
ITSN2
Intersectin 2.
    
 
 0.608
ap2a1
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
 
 0.577
rims2
Angiomotin like 1.
   
  
 0.557
aak1
Protein kinase domain-containing protein.
    
 
 0.553
ffar3
Amylase, alpha 2B (pancreatic); Belongs to the G-protein coupled receptor 1 family.
     
  0.540
nup188
Nucleoporin NUP188 homolog; May function as a component of the nuclear pore complex (NPC).
     
  0.540
hip1r
Uncharacterized protein.
    
 
 0.492
psmd10-2
Proteasome 26S subunit, non-ATPase 10.
    
 
 0.491
itsn1
Thiamin pyrophosphokinase 1.
    
 
 0.476
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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