STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nphp1Nuclear factor I C. (687 aa)    
Predicted Functional Partners:
RPGRIP1L
RPGRIP1 like.
    
 
 0.891
iqcb1
Uncharacterized protein.
    
 
 0.803
tmem237
Transmembrane protein 237; Component of the transition zone in primary cilia. Required for ciliogenesis (By similarity); Belongs to the TMEM237 family.
   
 
 0.802
nphp4.2
Vac14 homolog.
   
 
 0.801
slc6a19-2
Solute carrier family 6 (neutral amino acid transporter), member 19.
   
 
 0.801
b9d1
B9 domain-containing protein 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
      
 0.794
tmem67
Sideroflexin 5.
   
  
 0.769
CEP290
Centrosomal protein 290.
   
 
 0.768
tmem216
Polycystin 1, transient receptor potential channel interacting.
      
 0.761
AHI1
Abelson helper integration site 1.
    
 
 0.754
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.