STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psma4Proteasome subunit alpha type. (261 aa)    
Predicted Functional Partners:
psmc6
AAA domain-containing protein; Belongs to the AAA ATPase family.
  
 
 0.999
psmc1
Proteasome (Prosome, macropain) 26S subunit, ATPase, 1; Belongs to the AAA ATPase family.
   
 0.999
psma5
Proteasome subunit alpha type.
  
0.999
psmb4
Proteasome subunit beta; Belongs to the peptidase T1B family.
   
 
 0.999
psma2
Proteasome subunit alpha type.
   
0.999
psmb1
Proteasome subunit beta.
   
 0.999
psmd11
26S proteasome non-ATPase regulatory subunit 11; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. P [...]
   
 0.999
psmc5
Microtubule associated protein 7; Belongs to the AAA ATPase family.
   
 0.999
psmb2
Proteasome subunit beta.
   
 
 0.999
psma3
Proteasome subunit alpha type.
  
 
0.999
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.