STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC734020Uncharacterized protein. (495 aa)    
Predicted Functional Partners:
pdia6
Methyltransferase like 16; Belongs to the protein disulfide isomerase family.
   
 
 0.755
hspa5
Neuronal vesicle trafficking associated 1; Belongs to the heat shock protein 70 family.
  
 0.750
hsp90b1
Heat shock protein 90kDa beta (Grp94), member 1.
  
 
 0.748
sec63
Paired box 2.
   
 
 0.716
atg16l1
Autophagy-related protein 16; Plays an essential role in autophagy: interacts with ATG12- ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane; Belongs to the WD repeat ATG16 family.
     
  0.700
MAST4
Microtubule associated serine/threonine kinase family member 4.
     
  0.700
hyou1
Hypoxia up-regulated protein 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding; Belongs to the heat shock protein 70 family.
  
 0.655
hspa9
Heat shock 70kDa protein 9 (Mortalin); Belongs to the heat shock protein 70 family.
  
 0.640
ankrd45
Dopamine receptor D1.
  
 0.603
manf
Uncharacterized protein.
   
 
 0.600
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.