STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRAFB-Raf proto-oncogene, serine/threonine kinase. (908 aa)    
Predicted Functional Partners:
map2k1
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the protein kinase superfamily.
   
0.992
raf1
Zona pellucida glycoprotein 4.
  
 
0.966
or2t29
Olfactory receptor family 2 subfamily T member 29.
    
0.965
rap1b
Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family.
   
 0.949
nras
Novel gene of the neuroblastoma RAS viral (V-ras) oncogene homolog family.
   
 0.949
hras
Chloride channel accessory 1 gene 1.
   
 0.949
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.949
rap1a
Aldehyde dehydrogenase 1 family member A3.
   
 0.949
rras
Transducin like enhancer of split 1.
   
 0.935
mras
Thrombospondin 3.
   
 0.933
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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