STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F13A1Coagulation factor XIII A chain. (738 aa)    
Predicted Functional Partners:
chuk
Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.
   
 
  0.900
p3h1
Fe2OG dioxygenase domain-containing protein.
      
 0.662
igsf11
GTP binding protein 2.
      
 0.631
tnc
Adenylate cyclase activating polypeptide 1 (pituitary).
    
 
 0.612
F13B
Coagulation factor XIII B chain.
    
 
 0.549
LOC101735054
C-type lectin domain-containing protein.
    
 
 0.517
GAPVD1
GTPase activating protein and VPS9 domains 1.
    
 
 0.466
aspm
LDL receptor related protein 8.
      
 0.462
LOXHD1
Lipoxygenase homology domains 1.
    
 
 0.461
CYTL1
Cytokine like 1.
      
 0.459
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.