node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CIAO2A | c9orf64-2 | ENSXETP00000035499 | ENSXETP00000026162 | Cytosolic iron-sulfur assembly component 2A. | Queuosine salvage protein; Involved in salvaging queuosine. | 0.495 |
CIAO2A | ciao1 | ENSXETP00000035499 | ENSXETP00000034798 | Cytosolic iron-sulfur assembly component 2A. | Probable cytosolic iron-sulfur protein assembly protein ciao1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | 0.929 |
CIAO2A | ciao3 | ENSXETP00000035499 | ENSXETP00000002919 | Cytosolic iron-sulfur assembly component 2A. | Cytosolic Fe-S cluster assembly factor narfl; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the NARF family. | 0.528 |
CIAO2A | ercc2 | ENSXETP00000035499 | ENSXETP00000040494 | Cytosolic iron-sulfur assembly component 2A. | Epoxide hydrolase 3. | 0.670 |
CIAO2A | fbxl5 | ENSXETP00000035499 | ENSXETP00000027789 | Cytosolic iron-sulfur assembly component 2A. | F-box/LRR-repeat protein 5; Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of ireb2/irp2. Upon high iron and oxygen level, it specifically recognizes and binds ireb2/irp2, promoting its ubiquitination and degradation by the proteasome (By similarity). | 0.433 |
CIAO2A | ireb2 | ENSXETP00000035499 | ENSXETP00000049275 | Cytosolic iron-sulfur assembly component 2A. | Iron-responsive element-binding protein 2; RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA; Belongs to the aconitase/IPM isomerase family. | 0.441 |
CIAO2A | mms19 | ENSXETP00000035499 | ENSXETP00000031300 | Cytosolic iron-sulfur assembly component 2A. | MMS19 nucleotide excision repair protein homolog; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins (By similarity). | 0.885 |
CIAO2A | narf | ENSXETP00000035499 | ENSXETP00000046314 | Cytosolic iron-sulfur assembly component 2A. | TAP binding protein (tapasin); Belongs to the NARF family. | 0.528 |
c9orf64-2 | CIAO2A | ENSXETP00000026162 | ENSXETP00000035499 | Queuosine salvage protein; Involved in salvaging queuosine. | Cytosolic iron-sulfur assembly component 2A. | 0.495 |
ciao1 | CIAO2A | ENSXETP00000034798 | ENSXETP00000035499 | Probable cytosolic iron-sulfur protein assembly protein ciao1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | Cytosolic iron-sulfur assembly component 2A. | 0.929 |
ciao1 | ciao3 | ENSXETP00000034798 | ENSXETP00000002919 | Probable cytosolic iron-sulfur protein assembly protein ciao1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | Cytosolic Fe-S cluster assembly factor narfl; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the NARF family. | 0.920 |
ciao1 | ercc2 | ENSXETP00000034798 | ENSXETP00000040494 | Probable cytosolic iron-sulfur protein assembly protein ciao1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | Epoxide hydrolase 3. | 0.786 |
ciao1 | mms19 | ENSXETP00000034798 | ENSXETP00000031300 | Probable cytosolic iron-sulfur protein assembly protein ciao1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | MMS19 nucleotide excision repair protein homolog; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins (By similarity). | 0.990 |
ciao1 | narf | ENSXETP00000034798 | ENSXETP00000046314 | Probable cytosolic iron-sulfur protein assembly protein ciao1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | TAP binding protein (tapasin); Belongs to the NARF family. | 0.726 |
ciao3 | CIAO2A | ENSXETP00000002919 | ENSXETP00000035499 | Cytosolic Fe-S cluster assembly factor narfl; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the NARF family. | Cytosolic iron-sulfur assembly component 2A. | 0.528 |
ciao3 | ciao1 | ENSXETP00000002919 | ENSXETP00000034798 | Cytosolic Fe-S cluster assembly factor narfl; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the NARF family. | Probable cytosolic iron-sulfur protein assembly protein ciao1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | 0.920 |
ciao3 | ercc2 | ENSXETP00000002919 | ENSXETP00000040494 | Cytosolic Fe-S cluster assembly factor narfl; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the NARF family. | Epoxide hydrolase 3. | 0.415 |
ciao3 | mms19 | ENSXETP00000002919 | ENSXETP00000031300 | Cytosolic Fe-S cluster assembly factor narfl; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the NARF family. | MMS19 nucleotide excision repair protein homolog; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins (By similarity). | 0.884 |
ercc2 | CIAO2A | ENSXETP00000040494 | ENSXETP00000035499 | Epoxide hydrolase 3. | Cytosolic iron-sulfur assembly component 2A. | 0.670 |
ercc2 | ciao1 | ENSXETP00000040494 | ENSXETP00000034798 | Epoxide hydrolase 3. | Probable cytosolic iron-sulfur protein assembly protein ciao1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | 0.786 |