node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERCC4 | FANCM | ENSXETP00000032232 | ENSXETP00000028604 | ERCC excision repair 4, endonuclease catalytic subunit. | FA complementation group M. | 0.673 |
ERCC4 | NARS1 | ENSXETP00000032232 | ENSXETP00000036990 | ERCC excision repair 4, endonuclease catalytic subunit. | Asparaginyl-tRNA synthetase. | 0.870 |
ERCC4 | mus81 | ENSXETP00000032232 | ENSXETP00000025149 | ERCC excision repair 4, endonuclease catalytic subunit. | Crossover junction endonuclease MUS81; Interacts with eme1 and eme2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks (By similarity); Belongs to the XPF family. | 0.929 |
ERCC4 | slx1a | ENSXETP00000032232 | ENSXETP00000010035 | ERCC excision repair 4, endonuclease catalytic subunit. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. | 0.814 |
FANCM | ERCC4 | ENSXETP00000028604 | ENSXETP00000032232 | FA complementation group M. | ERCC excision repair 4, endonuclease catalytic subunit. | 0.673 |
FANCM | NARS1 | ENSXETP00000028604 | ENSXETP00000036990 | FA complementation group M. | Asparaginyl-tRNA synthetase. | 0.923 |
FANCM | mus81 | ENSXETP00000028604 | ENSXETP00000025149 | FA complementation group M. | Crossover junction endonuclease MUS81; Interacts with eme1 and eme2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks (By similarity); Belongs to the XPF family. | 0.999 |
FANCM | slx1a | ENSXETP00000028604 | ENSXETP00000010035 | FA complementation group M. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. | 0.806 |
NARS1 | ERCC4 | ENSXETP00000036990 | ENSXETP00000032232 | Asparaginyl-tRNA synthetase. | ERCC excision repair 4, endonuclease catalytic subunit. | 0.870 |
NARS1 | FANCM | ENSXETP00000036990 | ENSXETP00000028604 | Asparaginyl-tRNA synthetase. | FA complementation group M. | 0.923 |
NARS1 | eprs1 | ENSXETP00000036990 | ENSXETP00000048582 | Asparaginyl-tRNA synthetase. | Solute carrier family 12, member 9. | 0.998 |
NARS1 | gatb | ENSXETP00000036990 | ENSXETP00000016947 | Asparaginyl-tRNA synthetase. | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. | 0.987 |
NARS1 | gatc | ENSXETP00000036990 | ENSXETP00000014294 | Asparaginyl-tRNA synthetase. | Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. | 0.900 |
NARS1 | mars1 | ENSXETP00000036990 | ENSXETP00000020929 | Asparaginyl-tRNA synthetase. | WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.926 |
NARS1 | mus81 | ENSXETP00000036990 | ENSXETP00000025149 | Asparaginyl-tRNA synthetase. | Crossover junction endonuclease MUS81; Interacts with eme1 and eme2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks (By similarity); Belongs to the XPF family. | 0.855 |
NARS1 | qrsl1 | ENSXETP00000036990 | ENSXETP00000012373 | Asparaginyl-tRNA synthetase. | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. | 0.954 |
NARS1 | slx1a | ENSXETP00000036990 | ENSXETP00000010035 | Asparaginyl-tRNA synthetase. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. | 0.855 |
NARS1 | yars1 | ENSXETP00000036990 | ENSXETP00000027453 | Asparaginyl-tRNA synthetase. | Tyrosine--tRNA ligase, cytoplasmic; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). | 0.960 |
eprs1 | NARS1 | ENSXETP00000048582 | ENSXETP00000036990 | Solute carrier family 12, member 9. | Asparaginyl-tRNA synthetase. | 0.998 |
eprs1 | gatb | ENSXETP00000048582 | ENSXETP00000016947 | Solute carrier family 12, member 9. | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. | 0.984 |