STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISL1ISL LIM homeobox 1. (349 aa)    
Predicted Functional Partners:
gabra3
PHD finger protein 19.
 
 
 
 0.746
ENSXETP00000052435
LIM zinc-binding domain-containing protein.
   
 
0.671
ldb1
LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. Acts as a coactivator together with otx2 to stimulate lhx1/lim1-mediated activation of the gsc promoter in the Spemann organizer. Acts synergistically with lhx1/lim1 and ssbp in axis formation (By similarity).
    
 
 0.638
ldb2
Claudin 8, gene 1.
    
 
 0.638
nkx2-5
Toll-like receptor12.
      
 0.635
zfpm2
GPI mannosyltransferase 1.
    
 
 0.580
ets2
Protein C-ets-2; Transcription factor; Belongs to the ETS family.
    
 
 0.527
MEIS1
Meis homeobox 1.
    
 
 0.456
gata4
DNA replication licensing factor mcm4.
    
 
 0.440
BARX1
BARX homeobox 1.
   
 
 0.434
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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