STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppidPeptidylprolyl isomerase D (cyclophilin D) (370 aa)    
Predicted Functional Partners:
ptges3
Uncharacterized protein; Prostaglandin E synthase 3 (cytosolic)
   
 0.982
hsp90aa1.1
Heat shock protein 90kDa alpha (cytosolic), class A member 1, gene 1
   
 0.978
hsp90ab1
Heat shock protein 90kDa alpha (cytosolic), class B member 1
   
 0.978
ppp5c
Protein phosphatase 5, catalytic subunit
   
 0.950
fkbp4
Peptidylprolyl isomerase; FK506 binding protein 4, 59kDa
   
0.931
esr1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues
    
 0.921
mapk1
Mitogen-activated protein kinase 1
   
 0.914
esr2
Uncharacterized protein; Estrogen receptor 2 (ER beta)
    
 0.902
MGC75700
Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family
   
 0.864
ahsa1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1
   
 
 0.860
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. (Silurana) tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, Xenopus tropicalis, western clawed frog
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