STRINGSTRING
cep76 protein (Xenopus tropicalis) - STRING interaction network
"cep76" - Centrosomal protein of 76 kDa in Xenopus tropicalis
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cep76Centrosomal protein of 76 kDa; Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication (By similarity) (661 aa)    
Predicted Functional Partners:
ccp110
Centriolar coiled coil protein 110kDa (986 aa)
     
  0.992
cep97
Centrosomal protein 97kDa (809 aa)
     
  0.978
plk4
Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as sass6, cenpj/cpap, ccp110, cep135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Its central role in centriole replication suggests a possible role in tumorigenes [...] (951 aa)
     
  0.968
CEP63
Centrosomal protein 63kDa (606 aa)
         
  0.963
cep135
Centrosomal protein 135kDa (1177 aa)
     
 
  0.960
CEP164
Centrosomal protein 164kDa (1424 aa)
         
  0.960
cep78
Centrosomal protein of 78 kDa; May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis (727 aa)
     
  0.957
CEP192
Centrosomal protein 192kDa (1115 aa)
     
 
  0.955
PCNT
Uncharacterized protein; Pericentrin (2950 aa)
     
 
  0.952
cep152
Centrosomal protein 152kDa (1656 aa)
     
 
  0.948
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. (Silurana) tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, Xenopus tropicalis, western clawed frog
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