STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arhgef12Retinoic acid induced 2. (1438 aa)    
Predicted Functional Partners:
gna13
LOC100145489 protein.
    
 0.968
rhoa.2
Nuclear receptor binding SET domain protein 3.
   
 0.940
rhoa
Ras homolog gene family, member A.
   
 0.940
rhoc
Calponin 3, acidic.
   
 0.940
mras
Thrombospondin 3.
    
 0.914
nras
Novel gene of the neuroblastoma RAS viral (V-ras) oncogene homolog family.
    
  0.913
hras
Chloride channel accessory 1 gene 1.
    
  0.913
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
    
  0.913
rras
Transducin like enhancer of split 1.
    
  0.913
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.910
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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