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hdac8 protein (Xenopus tropicalis) - STRING interaction network
"hdac8" - Histone deacetylase 8 in Xenopus tropicalis
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
hdac8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) (369 aa)    
Predicted Functional Partners:
smc3
Structural maintenance of chromosomes 3 (1222 aa)
   
  0.981
wapal
WAPL cohesin release factor; Wings apart-like homolog (1181 aa)
     
 
  0.960
rad21
RAD21 cohesin complex component; RAD21 homolog (S. pombe) (644 aa)
     
  0.953
STAG2
Stromal antigen 2 (1276 aa)
     
  0.947
smc1a
Structural maintenance of chromosomes 1A (1235 aa)
   
  0.945
pds5b
Uncharacterized protein; PDS5, regulator of cohesion maintenance, homolog B (1449 aa)
     
  0.940
pds5a
PDS5, regulator of cohesion maintenance, homolog A (1320 aa)
     
  0.939
hist1h2aj
Histone cluster 1, H2aj (142 aa)
       
  0.923
stag1
Stromal antigen 1 (1266 aa)
     
  0.921
ENSXETG00000031135
Histone H2B (134 aa)
     
  0.917
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. (Silurana) tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, Xenopus tropicalis, western clawed frog
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