STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mpdzIntermediate filament family orphan 2. (2164 aa)    
Predicted Functional Partners:
mpp5
Uncharacterized protein; Belongs to the MAGUK family.
    
 0.971
AMOT
Angiomotin.
    
 0.933
amotl1
Phosphoenolpyruvate carboxykinase 1.
    
 0.933
AMOTL2
Angiomotin like 2.
   
 0.922
plcb4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
   0.529
mpp7
MAGUK p55 subfamily member 7; Acts as an important adapter that promotes epithelial cell polarity and tight junction formation. Involved in the assembly of protein complexes at sites of cell-cell contact (By similarity). Belongs to the MAGUK family.
    
 
 0.483
crb1
MSS51 mitochondrial translational activator.
    
 
 0.449
ANKRD33B
Ankyrin repeat domain 33B.
    
 
 0.444
tmc6
Transmembrane channel-like protein.
    
 
 0.434
TMC5
Transmembrane channel-like protein.
    
 
 0.434
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.