node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAP2 | GRXCR1 | ENSXETP00000049856 | ENSXETP00000018081 | Adenylyl cyclase-associated protein; Belongs to the CAP family. | Glutaredoxin and cysteine rich domain containing 1. | 0.711 |
CAP2 | PFN4 | ENSXETP00000049856 | ENSXETP00000021205 | Adenylyl cyclase-associated protein; Belongs to the CAP family. | Profilin; Belongs to the profilin family. | 0.784 |
CAP2 | PHLPP2 | ENSXETP00000049856 | ENSXETP00000001990 | Adenylyl cyclase-associated protein; Belongs to the CAP family. | PH domain and leucine rich repeat protein phosphatase 2. | 0.728 |
CAP2 | cfl1 | ENSXETP00000049856 | ENSXETP00000005783 | Adenylyl cyclase-associated protein; Belongs to the CAP family. | Cofilin-1; May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Required for formation of the cleavage furrow during cytokinesis. | 0.676 |
CAP2 | dbn1 | ENSXETP00000049856 | ENSXETP00000033514 | Adenylyl cyclase-associated protein; Belongs to the CAP family. | ADF-H domain-containing protein. | 0.777 |
CAP2 | dbnl | ENSXETP00000049856 | ENSXETP00000049921 | Adenylyl cyclase-associated protein; Belongs to the CAP family. | Adaptor related protein complex 2 subunit sigma 1. | 0.777 |
CAP2 | dstn | ENSXETP00000049856 | ENSXETP00000029510 | Adenylyl cyclase-associated protein; Belongs to the CAP family. | Solute carrier family 1 member 2; Belongs to the actin-binding proteins ADF family. | 0.676 |
CAP2 | phlpp1 | ENSXETP00000049856 | ENSXETP00000009790 | Adenylyl cyclase-associated protein; Belongs to the CAP family. | Cadherin 15. | 0.728 |
CAP2 | twf1 | ENSXETP00000049856 | ENSXETP00000002726 | Adenylyl cyclase-associated protein; Belongs to the CAP family. | Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin (By similarity). | 0.833 |
CAP2 | wdr1 | ENSXETP00000049856 | ENSXETP00000025497 | Adenylyl cyclase-associated protein; Belongs to the CAP family. | WD repeat-containing protein 1; Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Doesn't sever actin filaments alone, but caps the barbed ends of filaments severed by cofilin, which blocks annealing and depolymerization and allows more extensive severing by cofilin (By similarity); Belongs to the WD repeat AIP1 family. | 0.701 |
GRXCR1 | CAP2 | ENSXETP00000018081 | ENSXETP00000049856 | Glutaredoxin and cysteine rich domain containing 1. | Adenylyl cyclase-associated protein; Belongs to the CAP family. | 0.711 |
PFN4 | CAP2 | ENSXETP00000021205 | ENSXETP00000049856 | Profilin; Belongs to the profilin family. | Adenylyl cyclase-associated protein; Belongs to the CAP family. | 0.784 |
PFN4 | cfl1 | ENSXETP00000021205 | ENSXETP00000005783 | Profilin; Belongs to the profilin family. | Cofilin-1; May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Required for formation of the cleavage furrow during cytokinesis. | 0.736 |
PFN4 | dbn1 | ENSXETP00000021205 | ENSXETP00000033514 | Profilin; Belongs to the profilin family. | ADF-H domain-containing protein. | 0.523 |
PFN4 | dbnl | ENSXETP00000021205 | ENSXETP00000049921 | Profilin; Belongs to the profilin family. | Adaptor related protein complex 2 subunit sigma 1. | 0.523 |
PFN4 | dstn | ENSXETP00000021205 | ENSXETP00000029510 | Profilin; Belongs to the profilin family. | Solute carrier family 1 member 2; Belongs to the actin-binding proteins ADF family. | 0.736 |
PFN4 | twf1 | ENSXETP00000021205 | ENSXETP00000002726 | Profilin; Belongs to the profilin family. | Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin (By similarity). | 0.764 |
PFN4 | wdr1 | ENSXETP00000021205 | ENSXETP00000025497 | Profilin; Belongs to the profilin family. | WD repeat-containing protein 1; Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Doesn't sever actin filaments alone, but caps the barbed ends of filaments severed by cofilin, which blocks annealing and depolymerization and allows more extensive severing by cofilin (By similarity); Belongs to the WD repeat AIP1 family. | 0.676 |
PHLPP2 | CAP2 | ENSXETP00000001990 | ENSXETP00000049856 | PH domain and leucine rich repeat protein phosphatase 2. | Adenylyl cyclase-associated protein; Belongs to the CAP family. | 0.728 |
PHLPP2 | phlpp1 | ENSXETP00000001990 | ENSXETP00000009790 | PH domain and leucine rich repeat protein phosphatase 2. | Cadherin 15. | 0.493 |