STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnajc2DnaJ homolog subfamily C member 2; Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription ac [...] (635 aa)    
Predicted Functional Partners:
hspa14
Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state
   
 0.990
hspa4
Heat shock protein family a (hsp70) member 4; Heat shock 70kDa protein 4
   
 0.990
hspa1l
Heat shock protein family a (hsp70) member 1 like; Belongs to the heat shock protein 70 family
   
 0.967
hspa1b
Low quality protein: heat shock 70 kda protein; Belongs to the heat shock protein 70 family
   
 0.967
hspa8
Heat shock protein family a (hsp70) member 8; Belongs to the heat shock protein 70 family
   
 0.967
hspa2
Heat shock protein family a (hsp70) member 2; Belongs to the heat shock protein 70 family
   
 0.967
hsp70
Heat shock 70kDa protein
   
 0.967
hspa9
Heat shock protein family a (hsp70) member 9; Heat shock 70kDa protein 9 (mortalin)
   
 0.964
hspa13
Stress 70 protein chaperone microsome-associated 60kda protein; Heat shock protein 70kDa family, member 13
   
 0.959
hspa12b
Heat shock protein family a (hsp70) member 12b; Heat shock 70kD protein 12B
   
 0.959
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. (Silurana) tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, western clawed frog
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