STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrbMembrane metallo-endopeptidase-like 1. (478 aa)    
Predicted Functional Partners:
thra
Apolipoprotein A4.
  
  
0.903
rxrg
Glutamate receptor interacting protein 2.
    
 
0.608
rxra
Paralemmin.
    
 
0.608
rxrb
Uncharacterized protein.
    
 
0.608
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.591
ACOX3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
    
 0.562
rps4x
40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.
    
 0.561
alox12b
RNA guanylyltransferase and 5'-phosphatase.
    
  0.551
grhl2
Grainyhead-like protein 2 homolog; Transcription factor playing an important role in primary neurulation and in epithelial development. Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' acting as an activator and repressor on distinct target genes.
    
  0.547
SCML4
Scm polycomb group protein like 4.
    
  0.546
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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