STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scg3Secretogranin-3; Member of the granin protein family that regulates the biogenesis of secretory granules (By similarity). Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (By similarity). May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (By similarity). (461 aa)    
Predicted Functional Partners:
chgb
Inositol polyphosphate multikinase.
   
  
 0.656
scg2
BRX1, biogenesis of ribosomes.
   
  
 0.617
cpe
Uncharacterized protein.
   
  
 0.486
tac1
Olfactomedin 2; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family.
     
 0.422
zfpm2
GPI mannosyltransferase 1.
  
     0.421
tpp2
XPA binding protein 2.
   
 
 0.420
trpa1
Transient receptor potential ankyrin 1; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.418
rapgef2
Cathepsin K-like.
   
 
  0.417
DISP2
Dispatched RND transporter family member 2.
   
  
 0.417
rasgrf2
CTD small phosphatase 1.
   
 
  0.410
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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