node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LEO1 | SUPT6H | ENSXETP00000052878 | ENSXETP00000013264 | LEO1 homolog, Paf1/RNA polymerase II complex component. | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | 0.999 |
LEO1 | cdc73 | ENSXETP00000052878 | ENSXETP00000036442 | LEO1 homolog, Paf1/RNA polymerase II complex component. | Hyperparathyroidism 2 (With jaw tumor). | 0.999 |
LEO1 | ctr9 | ENSXETP00000052878 | ENSXETP00000025818 | LEO1 homolog, Paf1/RNA polymerase II complex component. | RNA polymerase-associated protein CTR9 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II (By similarity). PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). | 0.999 |
LEO1 | fancg-2 | ENSXETP00000052878 | ENSXETP00000030898 | LEO1 homolog, Paf1/RNA polymerase II complex component. | Solute carrier family 35 member F4. | 0.999 |
LEO1 | paf1 | ENSXETP00000052878 | ENSXETP00000004066 | LEO1 homolog, Paf1/RNA polymerase II complex component. | RNA polymerase II-associated factor 1 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). | 0.999 |
LEO1 | rtf1 | ENSXETP00000052878 | ENSXETP00000053832 | LEO1 homolog, Paf1/RNA polymerase II complex component. | Plus3 domain-containing protein. | 0.999 |
LEO1 | ssrp1 | ENSXETP00000052878 | ENSXETP00000026156 | LEO1 homolog, Paf1/RNA polymerase II complex component. | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] | 0.999 |
LEO1 | supt4h1 | ENSXETP00000052878 | ENSXETP00000005437 | LEO1 homolog, Paf1/RNA polymerase II complex component. | Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. | 0.999 |
LEO1 | supt5h | ENSXETP00000052878 | ENSXETP00000003515 | LEO1 homolog, Paf1/RNA polymerase II complex component. | Transcription elongation factor SPT5. | 0.930 |
LEO1 | wdr61 | ENSXETP00000052878 | ENSXETP00000015781 | LEO1 homolog, Paf1/RNA polymerase II complex component. | WD repeat-containing protein 61. | 0.964 |
SUPT6H | LEO1 | ENSXETP00000013264 | ENSXETP00000052878 | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | LEO1 homolog, Paf1/RNA polymerase II complex component. | 0.999 |
SUPT6H | cdc73 | ENSXETP00000013264 | ENSXETP00000036442 | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | Hyperparathyroidism 2 (With jaw tumor). | 0.944 |
SUPT6H | ctr9 | ENSXETP00000013264 | ENSXETP00000025818 | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | RNA polymerase-associated protein CTR9 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II (By similarity). PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). | 0.964 |
SUPT6H | fancg-2 | ENSXETP00000013264 | ENSXETP00000030898 | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | Solute carrier family 35 member F4. | 0.969 |
SUPT6H | paf1 | ENSXETP00000013264 | ENSXETP00000004066 | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | RNA polymerase II-associated factor 1 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). | 0.875 |
SUPT6H | rtf1 | ENSXETP00000013264 | ENSXETP00000053832 | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | Plus3 domain-containing protein. | 0.951 |
SUPT6H | ssrp1 | ENSXETP00000013264 | ENSXETP00000026156 | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] | 0.969 |
SUPT6H | supt4h1 | ENSXETP00000013264 | ENSXETP00000005437 | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. | 0.968 |
SUPT6H | supt5h | ENSXETP00000013264 | ENSXETP00000003515 | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | Transcription elongation factor SPT5. | 0.994 |
SUPT6H | wdr61 | ENSXETP00000013264 | ENSXETP00000015781 | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. | WD repeat-containing protein 61. | 0.589 |