node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DOCK1 | PTK2 | ENSXETP00000054300 | ENSXETP00000054367 | Dedicator of cytokinesis 1; Belongs to the DOCK family. | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.911 |
DOCK1 | ago2 | ENSXETP00000054300 | ENSXETP00000054507 | Dedicator of cytokinesis 1; Belongs to the DOCK family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.544 |
DOCK1 | baiap2 | ENSXETP00000054300 | ENSXETP00000027421 | Dedicator of cytokinesis 1; Belongs to the DOCK family. | Uncharacterized protein. | 0.576 |
DOCK1 | bcar1 | ENSXETP00000054300 | ENSXETP00000043234 | Dedicator of cytokinesis 1; Belongs to the DOCK family. | SH3 domain-containing protein. | 0.927 |
DOCK1 | crk | ENSXETP00000054300 | ENSXETP00000014157 | Dedicator of cytokinesis 1; Belongs to the DOCK family. | Multivesicular body subunit 12B. | 0.958 |
DOCK1 | kctd1 | ENSXETP00000054300 | ENSXETP00000008500 | Dedicator of cytokinesis 1; Belongs to the DOCK family. | Potassium channel tetramerization domain containing 1. | 0.597 |
DOCK1 | nhp2 | ENSXETP00000054300 | ENSXETP00000048272 | Dedicator of cytokinesis 1; Belongs to the DOCK family. | H/ACA ribonucleoprotein complex subunit 2-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). | 0.567 |
DOCK1 | rac1 | ENSXETP00000054300 | ENSXETP00000038979 | Dedicator of cytokinesis 1; Belongs to the DOCK family. | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). | 0.953 |
DOCK1 | rac2 | ENSXETP00000054300 | ENSXETP00000009938 | Dedicator of cytokinesis 1; Belongs to the DOCK family. | Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). | 0.953 |
DOCK1 | rac3 | ENSXETP00000054300 | ENSXETP00000024427 | Dedicator of cytokinesis 1; Belongs to the DOCK family. | NGFI-A binding protein 2 (EGR1 binding protein 2). | 0.953 |
PTK2 | DOCK1 | ENSXETP00000054367 | ENSXETP00000054300 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | Dedicator of cytokinesis 1; Belongs to the DOCK family. | 0.911 |
PTK2 | ago2 | ENSXETP00000054367 | ENSXETP00000054507 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.524 |
PTK2 | bcar1 | ENSXETP00000054367 | ENSXETP00000043234 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | SH3 domain-containing protein. | 0.970 |
PTK2 | crk | ENSXETP00000054367 | ENSXETP00000014157 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | Multivesicular body subunit 12B. | 0.902 |
PTK2 | kctd1 | ENSXETP00000054367 | ENSXETP00000008500 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | Potassium channel tetramerization domain containing 1. | 0.404 |
ago2 | DOCK1 | ENSXETP00000054507 | ENSXETP00000054300 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Dedicator of cytokinesis 1; Belongs to the DOCK family. | 0.544 |
ago2 | PTK2 | ENSXETP00000054507 | ENSXETP00000054367 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.524 |
ago2 | baiap2 | ENSXETP00000054507 | ENSXETP00000027421 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Uncharacterized protein. | 0.540 |
baiap2 | DOCK1 | ENSXETP00000027421 | ENSXETP00000054300 | Uncharacterized protein. | Dedicator of cytokinesis 1; Belongs to the DOCK family. | 0.576 |
baiap2 | ago2 | ENSXETP00000027421 | ENSXETP00000054507 | Uncharacterized protein. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.540 |