STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nmd3Nonsense-mediated mrna decay protein 3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit (504 aa)    
Predicted Functional Partners:
lsg1
Large 60s subunit nuclear export gtpase 1; Large subunit GTPase 1 homolog
   
 
 0.998
rsl24d1
Ribosomal L24 domain containing 1
   
 
 0.997
pa2g4
Uncharacterized protein; Proliferation-associated 2G4, 38kDa
   
 
 0.996
gtpbp4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit
  
 
 0.995
mrto4
Mrna turnover protein 4 homolog; Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes
   
 
 0.993
znf622
Uncharacterized protein; Zinc finger protein 622
   
 
 0.990
rpl10
Large subunit ribosomal protein l10e; Ribosomal protein L10
   
 
 0.985
ddx49
Probable atp-dependent rna helicase ddx49; Uncharacterized protein; DEAD (Asp-Glu-Ala-Asp) box polypeptide 49; Belongs to the DEAD box helicase family
   
 
 0.982
eif6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis
   
 
 0.981
xpo1
Exportin-1; Exportin 1 (CRM1 homolog)
   
 
 0.979
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. (Silurana) tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, western clawed frog
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