| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SYNW0281 | glmM | SYNW0281 | SYNW0282 | Possible soluble lytic transglycosylase. | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.555 |
| SYNW0450 | glmM | SYNW0450 | SYNW0282 | Putative sugar-phosphate nucleotide transferase. | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.598 |
| SYNW0450 | glmS | SYNW0450 | SYNW0145 | Putative sugar-phosphate nucleotide transferase. | Glutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.517 |
| SYNW0450 | manC | SYNW0450 | SYNW0148 | Putative sugar-phosphate nucleotide transferase. | GDP-mannose pyrophosphorylase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.637 |
| SYNW0450 | pykF | SYNW0450 | SYNW1298 | Putative sugar-phosphate nucleotide transferase. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.615 |
| SYNW2286 | glmM | SYNW2286 | SYNW0282 | Putative N-acetyl-glucosamine-6-phosphate deacetylase. | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.925 |
| SYNW2286 | glmS | SYNW2286 | SYNW0145 | Putative N-acetyl-glucosamine-6-phosphate deacetylase. | Glutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.937 |
| SYNW2286 | nagB | SYNW2286 | SYNW0540 | Putative N-acetyl-glucosamine-6-phosphate deacetylase. | Putative N-acetylglucosamine-6-phosphate isomerase. | 0.996 |
| dacA | glmM | SYNW0935 | SYNW0282 | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.618 |
| glmM | SYNW0281 | SYNW0282 | SYNW0281 | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Possible soluble lytic transglycosylase. | 0.555 |
| glmM | SYNW0450 | SYNW0282 | SYNW0450 | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Putative sugar-phosphate nucleotide transferase. | 0.598 |
| glmM | SYNW2286 | SYNW0282 | SYNW2286 | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Putative N-acetyl-glucosamine-6-phosphate deacetylase. | 0.925 |
| glmM | dacA | SYNW0282 | SYNW0935 | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.618 |
| glmM | glmS | SYNW0282 | SYNW0145 | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.936 |
| glmM | glmU | SYNW0282 | SYNW1003 | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.958 |
| glmM | manC | SYNW0282 | SYNW0148 | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | GDP-mannose pyrophosphorylase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.613 |
| glmM | murC | SYNW0282 | SYNW0029 | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Probable UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.559 |
| glmM | nagB | SYNW0282 | SYNW0540 | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Putative N-acetylglucosamine-6-phosphate isomerase. | 0.908 |
| glmM | pykF | SYNW0282 | SYNW1298 | Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.623 |
| glmS | SYNW0450 | SYNW0145 | SYNW0450 | Glutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Putative sugar-phosphate nucleotide transferase. | 0.517 |