STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BioAPutative diaminopelargonic acid synthase; Citation: Otsuka et al. (1988) J. Biol. Chem. 263:19577-19585; Kack et al. (1999) J. Mol. Biol. 291:857-876; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa)    
Predicted Functional Partners:
BioD
Putative Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 0.998
BioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 0.987
bioF
Putative 8-amino-7-oxononanoate synthase; Citation: Otsuka et al. (1988) J. Biol. Chem. 263:19577-19585; Alexeev et al. (1998) J. Mol. Biol. 284:401-419.
 
 
 0.986
SYNW0632
Conserved hypothetical protein; Possible SAM-dependent methyltransferase.
 
  
 0.654
trpC
Indole-3-glycerol phosphate synthase; Putative assignment; Belongs to the TrpC family.
      
 0.653
trpD/G
Putative Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
      
 0.644
trpE
Anthranilate synthase component I and chorismate binding enzyme.
      
 0.634
hypA2
Putative hydrogenase expression/formation protein HypA2.
      
 0.630
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
      
 0.630
SYNW0630
Hypothetical.
       0.572
Your Current Organism:
Synechococcus sp. WH 8102
NCBI taxonomy Id: 84588
Other names: S. sp. WH 8102, Synechococcus sp. WH8102
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