| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SYNW0645 | SYNW0650 | SYNW0645 | SYNW0650 | Putative glycosyltransferase family 2 protein. | Conserved hypothetical protein. | 0.601 |
| SYNW0645 | SYNW0651 | SYNW0645 | SYNW0651 | Putative glycosyltransferase family 2 protein. | Conserved hypothetical protein; Weakly similar orf in MIT9313. | 0.509 |
| SYNW0645 | mtnD | SYNW0645 | SYNW0652 | Putative glycosyltransferase family 2 protein. | Similar to methionine salvage pathway enzyme E-2/E-2; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.509 |
| SYNW0645 | rfbB | SYNW0645 | SYNW0646 | Putative glycosyltransferase family 2 protein. | dTDP-glucose-4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.912 |
| SYNW0645 | rfbC | SYNW0645 | SYNW0648 | Putative glycosyltransferase family 2 protein. | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | 0.942 |
| SYNW0645 | rfbD | SYNW0645 | SYNW0647 | Putative glycosyltransferase family 2 protein. | Putative dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | 0.932 |
| SYNW0645 | rmlA. | SYNW0645 | SYNW0649 | Putative glycosyltransferase family 2 protein. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.905 |
| SYNW0650 | SYNW0645 | SYNW0650 | SYNW0645 | Conserved hypothetical protein. | Putative glycosyltransferase family 2 protein. | 0.601 |
| SYNW0650 | SYNW0651 | SYNW0650 | SYNW0651 | Conserved hypothetical protein. | Conserved hypothetical protein; Weakly similar orf in MIT9313. | 0.648 |
| SYNW0650 | SYNW1078 | SYNW0650 | SYNW1078 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.675 |
| SYNW0650 | cobI/cbiL | SYNW0650 | SYNW0653 | Conserved hypothetical protein. | PRECORRIN-2 C20-METHYLTRANSFERASE; Cobalamin biosynthesis; Citation: Blanche et al. (1989) J. Bacteriol. 171:4222-4231; Roth et al. (1993) J. Bacteriol. 175:3303-3316; Belongs to the precorrin methyltransferase family. | 0.478 |
| SYNW0650 | csoS2 | SYNW0650 | SYNW1716 | Conserved hypothetical protein. | Putative carboxysome structural peptide CsoS2. | 0.500 |
| SYNW0650 | mtnD | SYNW0650 | SYNW0652 | Conserved hypothetical protein. | Similar to methionine salvage pathway enzyme E-2/E-2; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.648 |
| SYNW0650 | rfbB | SYNW0650 | SYNW0646 | Conserved hypothetical protein. | dTDP-glucose-4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.601 |
| SYNW0650 | rfbC | SYNW0650 | SYNW0648 | Conserved hypothetical protein. | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | 0.601 |
| SYNW0650 | rfbD | SYNW0650 | SYNW0647 | Conserved hypothetical protein. | Putative dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | 0.601 |
| SYNW0650 | rmlA. | SYNW0650 | SYNW0649 | Conserved hypothetical protein. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.601 |
| SYNW0651 | SYNW0645 | SYNW0651 | SYNW0645 | Conserved hypothetical protein; Weakly similar orf in MIT9313. | Putative glycosyltransferase family 2 protein. | 0.509 |
| SYNW0651 | SYNW0650 | SYNW0651 | SYNW0650 | Conserved hypothetical protein; Weakly similar orf in MIT9313. | Conserved hypothetical protein. | 0.648 |
| SYNW0651 | cobI/cbiL | SYNW0651 | SYNW0653 | Conserved hypothetical protein; Weakly similar orf in MIT9313. | PRECORRIN-2 C20-METHYLTRANSFERASE; Cobalamin biosynthesis; Citation: Blanche et al. (1989) J. Bacteriol. 171:4222-4231; Roth et al. (1993) J. Bacteriol. 175:3303-3316; Belongs to the precorrin methyltransferase family. | 0.561 |