STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpiA,Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (243 aa)    
Predicted Functional Partners:
pgk,
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 0.999
gap3
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.996
gap2
Glyceraldehyde 3-phosphate dehydrogenase (NADP+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.995
pgi
Glucose-6-phosphate isomerase.
 
 0.993
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.989
CbbA
Fructose-bisphosphate/sedoheptulose-1, 7-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.984
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
 0.978
pgmI
Phosphoglycerate mutase, co-factor-independent (iPGM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.964
tktA,
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.963
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.919
Your Current Organism:
Synechococcus sp. WH 8102
NCBI taxonomy Id: 84588
Other names: S. sp. WH 8102, Synechococcus sp. WH8102
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.