STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
cobOPossible cob(I)alamin adenosyltransferase; Citation: Lundrigan and Kadner (1989) J. Bacteriol. 171:154-161; Fonseca and Escalante-Semerena (2001) J. Biol. Chem. 276:32101-32108. (221 aa)    
Predicted Functional Partners:
cobB
Cobyric acid synthase CobB; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.972
CobS
Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.971
cobU/cobP
Putative cobinamide kinase; Citation: O' Toole and Excalante-Semerena (1995) J. Biol. Chem. 270:23560-23569; Thomas et al. (2000) J. Biol. Chem. 2275:27576-27586.
 
  
 0.969
cobD
Putative cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.957
CobN
Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087.
 
  
 0.947
cbiA,cobB
Putative Cobyrinic acid a,c-diamide synthase; BELONGS TO THE SIRTUIN FAMILY; Citation: Tsang and Escalante-Semerena (1996) J. Bacteriol. 178:7016-7019.
 
 
 0.941
SYNW0277
cob(I)alamin adenosyltransferase.
  
  
 
0.924
SYNW2052
Conserved hypothetical protein.
  
  
 
0.923
SYNW1749
Possible methyltransferase.
       0.811
SYNW1748
Phage integrase family; Conserved in three marine cyanobacterial genomes. in addition to BLAST hits contains the applicable subsitutions in the R-H-R-Y motif identified by Nunes-Duby et al 1998.
       0.798
Your Current Organism:
Synechococcus sp. WH 8102
NCBI taxonomy Id: 84588
Other names: S. sp. WH 8102, Synechococcus sp. WH8102
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