STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (1587 aa)    
Predicted Functional Partners:
MRVI1
Protein MRVI1.
    
 0.960
UY3_10051
Inositol 1,4,5-trisphosphate receptor type 2.
 
     0.946
UY3_15975
cAMP-dependent protein kinase catalytic subunit alpha.
    
 0.934
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.919
Calmodulin
Calmodulin; Belongs to the calmodulin family.
    
 0.918
UY3_03375
Calmodulin, striated muscle; Belongs to the calmodulin family.
    
 0.918
UY3_03374
Calmodulin, striated muscle; Belongs to the calmodulin family.
    
 0.918
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.916
PLCB3
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3.
    
 0.916
PLCB1
Phosphoinositide phospholipase C.
    
 0.916
Your Current Organism:
Chelonia mydas
NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.