STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UY3_10457Leptin receptor. (1161 aa)    
Predicted Functional Partners:
LEP
Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.
    
 0.915
UY3_18766
Tyrosine-protein kinase.
    
 0.783
JAK2
Tyrosine-protein kinase.
    
 0.783
UY3_13816
Pro-opiomelanocortin A.
      
 0.684
JAK1
Tyrosine-protein kinase.
    
 0.679
TYK2
Non-receptor tyrosine-protein kinase TYK2.
    
 0.632
SOCS3
Suppressor of cytokine signaling 3.
    
 0.624
UY3_17760
Tyrosine-protein kinase.
    
 0.611
UY3_19114
Pro-neuropeptide Y.
      
 0.593
STAT3
Signal transducer and activator of transcription.
    
 0.563
Your Current Organism:
Chelonia mydas
NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle
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