STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UY3_02172Cell division cycle and apoptosis regulator protein 1. (1118 aa)    
Predicted Functional Partners:
UY3_04085
Pre-mRNA-processing factor 40 like protein A.
   
 
  0.763
UY3_01865
Transcription elongation regulator 1.
   
 
  0.712
SIRT1
NAD-dependent deacetylase sirtuin-1.
    
 0.658
UY3_02508
U2 snRNP-associated SURP motif-containing protein.
   
  
 0.606
UY3_00559
Transcription elongation regulator 1-like protein.
   
 
  0.598
UY3_02173
Storkhead-box protein 1.
 
    
 0.585
RBM25
RNA-binding protein 25.
   
 
 0.565
UY3_12298
Putative RNA-binding protein 23.
   
 0.546
DDX5
Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.
   
 
 0.531
TOP1
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
   0.520
Your Current Organism:
Chelonia mydas
NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle
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