STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL3Kelch-like protein 3. (628 aa)    
Predicted Functional Partners:
CUL3
Cullin-3; Belongs to the cullin family.
    
 0.844
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.586
CUL1
Cullin-1; Belongs to the cullin family.
    
 0.540
RSPH3
Radial spoke head 3-like protein.
   
   0.521
MAD2L2
Mitotic spindle assembly checkpoint protein MAD2B.
    
   0.516
UBA3
NEDD8-activating enzyme E1 catalytic subunit isoform A.
     
 0.491
BBS9
Protein PTHB1 isoform B.
    
 0.490
UBE2M
NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.480
NUB1
NEDD8 ultimate buster 1.
    
   0.480
DCUN1D4
DCN1-like protein.
     
 0.478
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.